Results 81 to 90 of about 31,445 (293)

Laccase-mediated in situ oxidation of dopa for bio-inspired coloration of silk fabric

open access: yes, 2017
The mechanism of the biological coloration of silk fabric by laccase-mediated in situ oxidation of dopa is revealed.
Xuerong Fan   +5 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Investigation of Color Causing Minerals in Yellow-Red Colored Quartzite Jade Using the Synchrotron Radiation Technique

open access: yesYankuang ceshi, 2016
Jade-like cryptocrystalline-microcrystalline vein quartzite is called quartzite jade in the jewel business of China. Color is the main criteria for the value of quartzite jade, and therefore studying the coloration mechanism is very important for the ...
ZHANG Yong   +4 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Integrated analysis of metabolome and transcriptome reveals the molecular mechanism underlying different colors of Phyllanthus emblica L. fruit

open access: yesIndustrial Crops and Products
The rare red Phyllanthus emblica L. fruit, with its distinctive appeal and potential nutritional profile, holds promise as an ideal material for both fresh consumption and plant-derived health food sector.
Jiaqi Xiao   +8 more
doaj   +1 more source

Juvenile coloration of lizards

open access: yes, 2012
This work summarizes the current knowledge about the coloration of the lizards - the mechanism of colour creation, to color (pigments and structural colors) and hormonal influence on the body colour. It deals with the possible functions of the coloration
Bauerová, Anna
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Enzyme-based textile coloration [PDF]

open access: yes
Textile coloration is typically characterised as a resource intensive production process that requires the use of large amounts of water, high concentrations of processing chemicals, high temperatures and long processing times, commonly resulting in high
Smith, Edward   +3 more
core  

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