Results 61 to 70 of about 284,773 (249)
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Low flow practice for laparoscopic colorectal surgery in pediatric patients
Bali Journal of Anesthesiology, 2018 Low flow anaesthesia and laparoscopic techniques in pediatric patients are two of many developments in the modern medical field. Both techniques were established to support environmentally friendly, safe, and comfortable anaesthesia practices for ...
Tjokorda Gde Agung Senapathi +4 more
doaj +1 more source
Asian Journal of Medical Sciences, 2020 Background: Most of the bleeding in the lower gastrointestinal tract are usually located in the rectum, colon and terminal ileum. Colonoscopy is an invasive procedure used for both diagnostic and therapeutic purposes for detection of lower ...
Subash Bhattarai +3 more
doaj +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
New England Journal of Medicine, 2016 In his review article, Strum (March 17 issue)1 provides data on the overall prevalence of colorectal adenomas in the United States and risk factors for these lesions. It is well established that patients with Streptococcus bovis–group infective endocarditis are at high risk for colorectal cancer.2 Although a strong relationship between Enterococcus ...
Ester Castellsagué +8 more
openaire +7 more sources
, 2009 A family history of colorectal cancer may increase colorectal cancer risk by influencing adenoma growth or enhancing the formation of new lesions. Data of men from the prospective Health Professionals Follow-Up Study who underwent an endoscopy between ...
Wu, Kana +18 more
core +1 more source
A rare case of Amyand’s hernia presenting as an enterocutaneous fistula
Journal of Surgical Case Reports, 2010 The finding of the vermiform appendix in an inguinal hernia has an incidence of approximately 1%. The condition is given the eponymous name Amyand’s hernia. However in just 0.08% the condition is complicated by an acute appendicitis.
L Flood, KH Chang, OJ McAnena
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Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Association between TAS2R38 gene polymorphisms and colorectal cancer risk [PDF]
, 2011 Molecular sensing in the lingual mucosa and in the gastro-intestinal tract play a role in the detection of ingested harmful drugs and toxins. Therefore, genetic polymorphisms affecting the capability of initiating these responses may be critical for the ...
Stemmler, Susanne +23 more
core +1 more source
Revista Colombiana de Cirugía, 2007 El síndrome Peutz - Jeghers es una enfermedad con pólipos del colon con un patrón autosómico dominante, su tipo histológico es hamartomatoso y aunque es muy rara la transformación maligna, se ha postulado una secuencia hamartoma - carcinoma.
María Helena Gaitán Buitrago +7 more
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