Results 181 to 190 of about 1,124,548 (306)

Integrated Transcriptomics Reveals Evolutionary Trajectories and Cell Density‐Dependent Mechanisms in Aldosterone‐Producing Adenomas

open access: yesAdvanced Science, EarlyView.
Aldosterone‐producing adenomas (APAs) develop via two distinct paths: directly from adrenal zona glomerulosa (zG) cells, or stepwise from zG cells through aldosterone‐producing micronodules (APMs) before progressing to APAs. Advanced single‐cell and spatial analyses identified distinct cell states linked to oxidative stress and cell–cell interactions ...
Zhuolun Sun   +7 more
wiley   +1 more source

APC Mutations Are Not Confined to Hotspot Regions in Early-Onset Colorectal Cancer [PDF]

open access: gold, 2020
Alan Aitchison   +5 more
openalex   +1 more source

Tumor‐Derived CDC37 Inhibits Antigen Cross‐Presentation in Dendritic Cells and Impairs Anti‐Tumor Immunity in Breast Cancer

open access: yesAdvanced Science, EarlyView.
Extracellular vesicle (EV)‐packaged CDC37 are released from TMBhiCTLlo breast cancer cells with high CDC37 expression, and internalized into endo/phagosomes of dendritic cells (DCs). Within these compartments, CDC37 locked HSP90–antigen complex, preventing antigen release into the cytosol.
Ruxin Wang   +10 more
wiley   +1 more source

Cost of illness in patients with metastatic colorectal cancer [PDF]

open access: bronze, 2010
Xue Song   +5 more
openalex   +1 more source

The treatment strategy of R0 resection in colorectal cancer with synchronous para-aortic lymph node metastasis [PDF]

open access: gold, 2020
Hajime Ushigome   +11 more
openalex   +1 more source

TREM2‐Mediated Cholesterol Efflux in Macrophages Inhibits Anti‐Tumor Immunity via Limitation of CD4+ T and NK Cells

open access: yesAdvanced Science, EarlyView.
Impaired anti‐tumor immunity is mediated by TREM2 + macrophages in non‐small cell lung cancer. TREM2 + macrophages prevent anti‐tumor immunity depending on the limitation of CD4 + T and NK cells. TREM2 promotes cholesterol efflux via ABCA1 to limit the production of CX3CL1 in macrophages.
Yunhan Wang   +9 more
wiley   +1 more source

Serum untargeted metabolomics analysis of colorectal cancer. [PDF]

open access: yesBMC Cancer
Yi Y, Cao Y, Guo Y, Cui Y, Han C, Sun W.
europepmc   +1 more source

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