Results 181 to 190 of about 5,332,530 (372)
The Regulation of Trace Metal Elements in Cancer Ferroptosis
Advanced Biology, EarlyView.The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang +5 more
wiley +1 more source
Cell kinetic indicators of premalignant stages of colorectal cancer [PDF]
, 1985 Harry Bleiberg, Marc Buyse, P. Galand
openalex +1 more source
H2O2‐Generating Advanced Nanomaterials for Cancer Treatment
Advanced Functional Materials, EarlyView.H2O2‐generating nanoplatforms can exploit tumor redox imbalance for O2 and toxic reactive oxygen species generation, leading to hypoxia reversal, and apoptosis of cancer cells, respectively. This review highlights the mechanisms of these nanoplatforms, including exogenous H₂O₂ delivery, endogenous amplification, and metal peroxides, which leads to ...
Kiyan Musaie +8 more
wiley +1 more source
Chemotherapy as an Adjuvant to Surgery for Colorectal Cancer
, 1975 Walter Lawrence +7 more
openalex +2 more sources
Combination chemotherapy of advanced colorectal cancer utilizing 5-fluorouracil, semustine, dacarbazine, vincristine, and hydroxyurea: A phase III trial by the eastern cooperative oncology group (EST: 4275) [PDF]
, 1982 Paul F. Engstrom +4 more
openalex +1 more source
Pharmacogenomics and colorectal cancer
Annals of Oncology, 2004 The current methods of treating cancer patients with chemotherapeutics do not account for interpatient variability in the expression of particular target genes. This variability leads to unpredictable tumor responses and host toxicity. The approach we have taken is to determine gene expression levels in the metabolic pathways of drugs used in the ...
openaire +4 more sources
Advanced Healthcare Materials, EarlyView.Schematic illustration of the mechanism of targeted delivery of nanoparticles including 1) paracellular, 2) endolysosomal escape, 3) receptor mediated endocytosis, and 4) M cell mediated transport for non‐GI diseases by oral administration such as atherosclerosis, cancer, diabetes, and brain diseases. Abstract Oral drug delivery is a promising approach
Subarna Ray +2 more
wiley +1 more source
Europe Against Cancer European Commission Series for General Practitioners, 1993 J. Hardcastle
semanticscholar +1 more source
Prognostic factors of advanced colorectal cancer patients receiving cytotoxic chemotherapy [PDF]
, 1986 Manfred Heim +3 more
openalex +1 more source