Results 201 to 210 of about 5,289,946 (346)

NFS1 Regulates IDH2 to Attenuate Abdominal Aortic Aneurysms via Interacting With SP2

Advanced Science, EarlyView.
The loss of NFS1 leads to its reduced binding with the transcription factor SP2, resulting in decreased expression of the downstream gene Idh2. This causes a shift in energy supply toward glycolysis in VSMCs, ultimately contributing to the occurrence and progression of AAA.
Luzheng Zhang, Yu Zhang, Dezhong Wen, Suxiang Guo, Xiaohui Qi, Heng Wang, Yujin Sun, Guangdong Yang, Yuehong Wang, Song Xue   +9 more
wiley   +1 more source

On Gender-Specific FIT Cutoffs in the Swedish Colorectal Cancer Screening Program. [PDF]

United European Gastroenterol J
Brenner H, Ola I, Seum T.
europepmc   +1 more source

Integrated Transcriptomics Reveals Evolutionary Trajectories and Cell Density‐Dependent Mechanisms in Aldosterone‐Producing Adenomas

Advanced Science, EarlyView.
Aldosterone‐producing adenomas (APAs) develop via two distinct paths: directly from adrenal zona glomerulosa (zG) cells, or stepwise from zG cells through aldosterone‐producing micronodules (APMs) before progressing to APAs. Advanced single‐cell and spatial analyses identified distinct cell states linked to oxidative stress and cell–cell interactions ...
Zhuolun Sun, Changying Jing, Martina Tetti, Siyuan Gong, Jia Wei, Yingxian Pang, Martin Reincke, Tracy Ann Williams   +7 more
wiley   +1 more source

An Integrative Roadmap for Advancing Colorectal Cancer Organoid. [PDF]

Biomedicines
Zhu Y, He K, Shi Z.
europepmc   +1 more source

K-ras mutations and benefit from cetuximab in advanced colorectal cancer.

New England Journal of Medicine, 2008
C. Karapetis, S. Khambata-Ford, D. Jonker, C. O'Callaghan, D. Tu, N. Tebbutt, R. Simes, H. Chalchal, J. Shapiro, S. Robitaille, T. Price, L. Shepherd, H. Au, C. Langer, M. Moore, J. Zalcberg   +15 more
semanticscholar   +1 more source

ETV4 interacts with LOXL2 to induce epigenetic activation of NID1 during colorectal cancer progression [PDF]

Tinghui Jiang, Xin Liu, Hao Liu, Kailong Du, Sen Wang, Hui Fan, Ying E. Zhang, Lin Cui, Hewei Zhang, Chun‐Dong Zhang, Yong Xia Zhu, Zhongyu Liu, Youquan Bu, Yunlong Lei   +13 more
openalex   +1 more source

FAPα+ Macrophages Orchestrate Immune Evasion in Multiple Myeloma by Dual Regulation of PD‐L1 and T Cell Senescence

Advanced Science, EarlyView.
ABSTRACT Multiple myeloma (MM) is a hematologic malignancy driven by clonal expansion of malignant plasma cells. Despite the long‐term disease control achieved with immunotherapies in some patients, treatment resistance remains a major cause of disease relapse.
Huiyao Gu, Zhenfeng Dai, Xi Huang, Enfan Zhang, Xinyuan Dai, Haoguang Chen, Wen Cao, Jinna Zhang, Yifan Hou, Haimeng Yan, Yang Yang, Li Yang, Yi Li, Wenlong Lin, Zhen Cai, Jingsong He   +15 more
wiley   +1 more source

Emergency presentation of colorectal cancer in Africa: a scoping review. [PDF]

BMJ Open
Chinyowa S, Murewanhema G, Katsidzira L, Moodley J, Chirenje M, Muguti G.   +5 more
europepmc   +1 more source

Mouse Macrophage galactose-type lectin (mMGL)1 receptor exhibits immunosuppressive and inflammatory properties in colorectal cancer 4000 [PDF]

Miriam Rodríguez‐Sosa, Sonia Elizabeth Hern ndez Navia, Imelda Juárez‐Avelar, Mario Alberto Tonathiu Rodriguez-Hernandez, Betsaida J. Ortiz‐Sánchez, Luis I. Terrazas   +5 more
openalex   +1 more source

Interleukin-22 and <italic>Fusobacterium nucleatum</italic> cooperate in promoting colorectal cancer [PDF]

, 2018
Jing‐Yuan Fang, Yingxuan Chen, Tingting Yan, Fangfang Guo, Jie Hong, Shiyuan Lu   +5 more
openalex   +1 more source