Results 211 to 220 of about 1,124,548 (306)

Immunogenicity and Optimal Timing of 13-Valent Pneumococcal Conjugate Vaccination during Adjuvant Chemotherapy in Gastric and Colorectal Cancer: A Randomized Controlled Trial [PDF]

, 2019
Wonyoung Choi, Jong Gwang Kim, Seung‐Hoon Beom, Jun‐Eul Hwang, Hyun-Jung Shim, Sang‐Hee Cho, Min‐Ho Shin, Sin‐Ho Jung, Ik-Joo Chung, Joon Young Song, Woo Kyun Bae   +10 more
openalex   +1 more source

Metformin Impairs Breast Cancer Growth through the Inhibition of PRMT6

Advanced Science, EarlyView.
Metformin has a biological activity against breast cancer. However, it is largely unknown about its precise therapeutic targets. Here, histone arginine methyltransferase PRMT6 is identified as a new anti‐cancer target for metformin. Metformin directly binds PRMT6 and inhibits its ability to catalyze histone H3R2 asymmetric dimethylation (H3R2me2a ...
Yinsheng Wu, Xinlin Xu, Yue Tong, Min Wang, Feng Ge, Min Wu, Yunlong Wang, Gang Chen, Xilan Yu, Shanshan Li   +9 more
wiley   +1 more source

Social Burden and Healthcare Costs of Colorectal Cancer. [PDF]

Cancers (Basel)
Gąska I, Czerw A, Pajewska M, Partyka O, Deptała A, Badowska-Kozakiewicz A, Czerw N, Mękal D, Sygit K, Malikowska K, Drobnik J, Pobrotyn P, Waśko-Czopnik D, Sowiński T, Bandurska E, Ciećko W, Grochans E, Cybulska AM, Schneider-Matyka D, Rachubińska K, Iltchev P, Czapla T, Kozlowski R.   +22 more
europepmc   +1 more source

HPD is an m6A Methyltransferase that Protects Colorectal Cancer Cells from Ferroptotic Cell Death by m6A Methylating SLC7A11/GPX4

Advanced Science, EarlyView.
This study reveals that the tyrosine metabolic enzyme HPD functions as a previously uncharacterized, METTL3‐independent m6A methyltransferase. It promotes colorectal tumor progression by coordinately regulating the SLC7A11/GPX4 axis to suppress ferroptosis.
Jiyan Wang, Xintong Dai, Huanle Liu, Saiwei Hua, Hongkai Chang, Huanran Sun, Mingming Sun, Huifang Zhao, Kemin Ni, Fei Xie, Yaya Qiao, Qingle Gao, Chenxi Yu, Qijun Zhang, Jianshuang Guo, Chunze Zhang, Shuai Zhang, Changliang Shan   +17 more
wiley   +1 more source

Colorectal cancer incidence, survival analysis and predictions (Monastir, Tunisia: 2002-2030). [PDF]

PLoS One
Bennasrallah C, Maatouk A, Kacem M, Dhouib W, Abroug H, Fredj MB, Safer L, Zaied S, Mokni M, Bouanène I, Belguith Sriha A, Zemni I.   +11 more
europepmc   +1 more source

A Longitudinal Study of Post-Traumatic Growth and Psychological Distress in Colorectal Cancer Survivors

, 2015
Stefano Occhipinti, Suzanne K. Chambers, Stephen J. Lepore, Joanne F. Aitken, Jeff Dunn   +4 more
openalex   +2 more sources

Procyanidin Capsules Combat ALF by Restoring Mitochondrial Homeostasis and Inhibiting Necroptosis via the PGAM5/DRP1/PINK1 Pathway

Advanced Science, EarlyView.
A biomimetic self‐assembly strategy, Procyanidin Capsules (PC‐Ca), has been developed, which has great stability, bioavailability, and liver‐targeting efficacy and modulates the KEAP1‐NRF2 axis to inhibit ROS formation and necroptosis, regulate mitochondrial homeostasis through the PGAM5/DRP1/PINK1 signaling pathway in thioacetamide (TAA)‐induced ALF ...
Qing Shi, Minmin Wu, Jinwei Zhong, Chao Chen, Zhuang Huang, Jingxuan Peng, Dong Yang, Xingjie Zan, Zhengfei Wang   +8 more
wiley   +1 more source

Accounting for Endoscopic Screening in Colorectal Cancer Risk Models. [PDF]

Cancer Epidemiol Biomarkers Prev
Wei EK, Wu K, Colditz GA, Giovannucci E, Chan AT, Song M, Rosner BA.   +6 more
europepmc   +1 more source

The “sphere of care”: A qualitative study of colorectal cancer patient and caregiver experiences of support within the cancer treatment setting

, 2018
Eleanor Law, Janelle Veronica Levesque, Sylvie Lambert, Afaf Girgis   +3 more
openalex   +2 more sources

Retinoic Acid Reprograms Mast Cells Toward a Proinflammatory State to Enhance Antitumor Immunity

Advanced Science, EarlyView.
Proinflammatory mast cells represent an MHC‐IIhigh, cytokine‐producing mast cell subset associated with improved survival and enhanced responses to anti‐PD‐1 therapy. Retinoic acid drives their polarization, enabling antigen uptake and presentation, and T cell recruitment and activation, collectively promoting adaptive anti‐tumor immunity.
Lizao Zhang, Siqi Ren, Yuhui Li, Rongxi Chen, Ling Qiu, Yongmei Tan, Suling Chen, Huiqian Wu, Lianxi Mai, Xiao Tan, Xin Liu, Peisheng Liang, Shijia Kuang, Liansheng Wang, Jingkang Liu, Jintao Li, Yanyan Li, Qiuping Xu, Yongzhi Su, Yuehai Luo, Binyan Wu, Zijing Huang, Haotian Cao, Qunxing Li, Jinsong Li, Tianjun Lan   +25 more
wiley   +1 more source