Results 211 to 220 of about 5,673,125 (350)

Clinical significance of BRAF non-V600E mutations on the therapeutic effects of anti-EGFR monoclonal antibody treatment in patients with pretreated metastatic colorectal cancer: the Biomarker Research for anti-EGFR monoclonal Antibodies by Comprehensive Cancer genomics (BREAC) study [PDF]

, 2017
Eiji Shinozaki, Takayuki Yoshino, Kentaro Yamazaki, Kei Muro, Kensei Yamaguchi, Tomohiro Nishina, Satoshi Yuki, Kohei Shitara, Hideaki Bando, Sachiyo Mimaki, Chikako Nakai, Koutatsu Matsushima, Yutaka Suzuki, Kiwamu Akagi, Takeharu Yamanaka, Shogo Nomura, Satoshi Fujii, Hiroyasu Esumi, Masaya Sugiyama, Nao Nishida, Masashi Mizokami, Yasuhiro Koh, Yukiko Abe, Atsushi Ohtsu, Katsuya Tsuchihara   +24 more
openalex   +1 more source

CCL5hi Macrophages Interact with CD8+ T Cells and Potentiate Responsiveness to PD‐1 Blockade Plus Chemotherapy in Esophageal Squamous Cell Carcinoma

Advanced Science, EarlyView.
This study has characterized a functionally distinct macrophage subset, termed CCL5hi macrophages, and elucidated the underlying mechanisms of a regulatory feedback loop that interconnects IFN‐γ, CCL5hi macrophages, and CD8+ T cells within the TME of ESCC undergoing immunochemotherapy.
Yuanzhen Ma, Xiaodong Su, Tingting Zeng, Chunlian Zhou, Guozhen Yang, Zengfei Xia, Chufeng Zeng, Jiarong Zhan, Xin‐Yuan Guan, Xu Zhang, Yan Li   +10 more
wiley   +1 more source

The genomic and transcriptomic landscapes of clock genes reveal the significance of circadian rhythm in the progression and immune microenvironment of metastatic colorectal cancer

Clinical and Translational Medicine, 2022
Long Zhang, Yikuan Chen, Choon Seng Chong, Xiaoji Ma, Shanyou Tong, Xingfeng He, Yiwei Li, Sanjun Cai, Shaobo Mo, Junjie Peng, Xiang Hu   +10 more
doaj   +1 more source

Biomarkers for colorectal cancer detection: An insight into colorectal cancer and FDA-approved biomarkers. [PDF]

Bioimpacts
Zamanian MY, Darmadi D, Darabi R, Fanoukh Aboqader Al-Aouadi R, Sadeghi Ivraghi M, Küpeli Akkol E.   +5 more
europepmc   +1 more source

Figure S5 from Residential Segregation and Colorectal Cancer Screening in the United States, 2010 to 2018 [PDF]

Eduardo J. Santiago‐Rodríguez, Salma Shariff‐Marco, Zinzi Bailey, Justin S. White, Isabel Elaine Allen, Robert A. Hiatt   +5 more
openalex   +1 more source

FBXO44 Regulates FOXP1 Degradation Through AURKA‐Dependent Phosphorylation to Promote Colorectal Cancer Progression

Advanced Science, EarlyView.
FBXO44 promotes colorectal cancer progression by targeting FOXP1 for ubiquitin‐mediated degradation. This study reveals a phosphorylation‐dependent mechanism involving AURKA and highlights the FBXO44/FOXP1/Cyclin E2 axis as a potential therapeutic target in colorectal cancer.
Hongxu Nie, Hengjie Xu, Sheng Yang, Chuanxin Tian, Tuo Wang, Chi Jin, Zhihao Chen, Xiaowei Wang, Junwei Tang, Yifei Feng, Yueming Sun   +10 more
wiley   +1 more source

Prkci acts a pro-proliferation factor in colorectal cancer. [PDF]

NPJ Precis Oncol
Li P, Liu G, Zhang W, Li T.
europepmc   +1 more source

Steroid Receptor Coactivator‐1 Drives Tumor‐Associated Macrophage Reprogramming by Mediating MMP12 Transcription in Pancreatic Cancer Perineural Invasion

Advanced Science, EarlyView.
Steroid receptor coactivator‐1 (SRC‐1) reprograms tumor‐associated macrophages (TAMs) via signal transducer and activator of transcription 1(STAT1)‐mediated matrix metallopeptidase 12 (MMP12) transcription to drive perineural invasion (PNI) in pancreatic cancer.
Ke Cheng, Liang Liu, Miaomiao Gong, Yuke Ji, Chunmei Bai, Xiangqian Guo, Hui Chen, Jinjin Pan, Ying Zhang, Yuhui Yuan   +9 more
wiley   +1 more source

In situ forming hydrogels for colorectal cancer therapy. [PDF]

Mater Today Bio
Yao Q, Shi Y, Yao Y, Zhao Y, Duan B, Kou L.   +5 more
europepmc   +1 more source

Detection of circulating tumor DNA by tumor-informed whole-genome sequencing enables prediction of recurrence in stage III colorectal cancer patients

Amanda Frydendahl, Jesper Nors, Mads H. Rasmussen, Tenna Vesterman Henriksen, Marijana Nesic, Thomas Reinert, Danielle Afterman, Tomer Lauterman, Maja Kuzman, Santiago González, Dunja Glavaš, James Smadback, Dillon Maloney, Jurica Levativ, Michael Yahalom, Ryan Ptashkin, Iman Tavassoly, Zohar Donenhirsh, Eric J. White, Kandasamy Ravi, Ury Alon, Iver Nordentoft, Sia V. Lindskrog, Lars Dyrskjøt, Claudia Jaensch, Uffe S. Løve, Per Vadgaard Andersen, Ole Thorlacius‐Ussing, Lene H. Iversen, Kåre Andersson Gotschalck, Asaf Zviran, Boris Oklander, Claus L. Andersen   +32 more
openalex   +1 more source