Results 231 to 240 of about 1,124,548 (306)

KHK-A promotes fructose-dependent colorectal cancer liver metastasis by facilitating the phosphorylation and translocation of PKM2

Chaofan Peng, Peng Yang, Dongsheng Zhang, Chi Jin, Wen Peng, Tuo Wang, Qingyang Sun, Zhihao Chen, Yifei Feng, Yueming Sun   +9 more
openalex   +1 more source

CD168 Identifies Proliferating Pancreatic Islet Cells in Murine and Human

Advanced Science, EarlyView.
This study identifies CD168 as a conserved surface marker for proliferating β‐cells in mouse, human islets, and pancreatic islet tumors. CD168⁺ cells show high proliferation and low insulin expression. CD168+ cells form mostly uni‐β lineage clones, and some of the clones are multi‐lineage.
Shubo Yuan, Jiafu Li, Min Shao, Haili Bao, Ajun Geng, Jialin Yang, Yu Tao, Xinyi Chen, Tianxiong Xiao, Chunye Liu, Zhiyao Xie, Wenqian Song, Qing Cissy Yu, Hongxing Fu, Xu Han, Taochen He, Wenquan Wang, Jianfeng Chen, Sheng Yan, Shaohua Song, Liang Liu, Yi Arial Zeng   +21 more
wiley   +1 more source

Five-Year Experience of Nationwide Implementation of Colorectal Cancer Screening in Sweden. [PDF]

United European Gastroenterol J
Hreinsson JP, Pischel A, Pålsson B, National Working Group for Colorectal Cancer Screening in Sweden (NWGCRCSS), Blom J.   +4 more
europepmc   +1 more source

ACSL5 Regulates Glucose Metabolism and Chemotherapy Sensitivity in Colorectal Cancer Cells under Glutamine Deficiency

Advanced Science, EarlyView.
Glutamine deprivation triggers ACSL5 upregulation in tumor cells, sustaining their viability via dual metabolic rewiring programs. ACSL5 enhances glycolysis by relieving p53's inhibition of PGAM1 while also sustaining mitochondrial respiration and TCA cycle flux through promoting IDH2 dimerization.
Shuai Tian, Qiaoxia Zhang, Xuedan Sun, Rick Francis Thorne, Zeyuan Shi, Qiang Ji, Zhangran Sun, Yuanxiang Lu, Qun Zhao, Xianjun Yu, Wanglai Hu, Mian Wu   +11 more
wiley   +1 more source

Expression and Clinical Significance of CD47 in Colorectal Cancer: A Review. [PDF]

Cancers (Basel)
Li Q, Vignali P, Tang D, Martinelli G, Fuochi B, Sparavelli R, Poma AM, Bruno R, Macerola E, Ugolini C.   +9 more
europepmc   +1 more source

A review of tumor-specific fluorescence-guided surgery for colorectal cancer

, 2020
Hannah M. Hollandsworth, Michael A. Turner, Robert M. Hoffman, Michael Bouvet   +3 more
openalex   +2 more sources

Single‐Position Peptide Clustering for Peptidomics Reveals Novel Disease Biomarkers and Dysregulated Proteolytic Characteristics

Advanced Science, EarlyView.
A novel amino acid (aa)‐score‐based single‐position peptide clustering strategy is developed for peptidomics, enabling precise profiling of protein proteolysis in plasma from β‐thalassemia cohort. The method identifies new aa position‐based peptide cluster biomarkers validated by heavy‐labeled peptides, visualizes aggregated changes, uncovers disease ...
Na Li, Yaxin Zhu, Yumeng Yan, Jifeng Wang, Lili Niu, Xiang Ding, Mengmeng Zhang, Zhensheng Xie, Tanxi Cai, Xiaojing Guo, Jianming Luo, Peng An, Xiangqian Guo, Fuquan Yang   +13 more
wiley   +1 more source

TYK2 Promotes Immunosurveillance of Colorectal Cancer Liver Metastasis. [PDF]

Cancer Res
Mödl B, Zwolanek D, Schwertner K, Krauß D, Moritsch S, Scharf I, Ebner AS, Moreno-Viedma V, de Sa Fernandes C, Novoszel P, Holcmann M, Hammer M, Matrone N, Schlederer M, Strobl B, Casanova E, Lassnig C, Herndler-Brandstetter D, Kenner L, Müller M, Sibilia M, Eferl R.   +21 more
europepmc   +1 more source

Correlation between chemosensitivity and mRNA expression level of 5-fluorouracil-related metabolic enzymes during liver metastasis of colorectal cancer

, 2006
Kenji Okumura, Hisanori Shiomi, Eiji Mekata, Machiko Kaizuka, Yoshihiro Endo, Yoshimasa Kurumi, Tohru Tani   +6 more
openalex   +2 more sources

Foundation Model‐Enabled Multimodal Deep Learning for Prognostic Prediction in Colorectal Cancer with Incomplete Modalities: A Multi‐Institutional Retrospective Study

Advanced Science, EarlyView.
FLARE, a multimodal AI framework, combines pathology slides, radiology scans, and clinical reports to predict colorectal cancer outcomes, even when some tests are missing. Evaluated retrospectively in 1679 patients from four medical centers, it consistently achieved the best prognostic accuracy and clearly separated high‐ and low‐risk groups.
Linhao Qu, Chengsheng Zhang, Yingyong Hou, Feng Tang, Weiqi Sheng, Dan Huang, Zhijian Song   +6 more
wiley   +1 more source