Results 261 to 270 of about 5,289,946 (346)

Small Nucleolar RNA Snord17 Promotes Self‐Renewal of Intestinal Stem Cells through Yy2 mRNA Export and Tead4 Activation

Advanced Science, EarlyView.
Snord17, through interaction with Thoc3, promotes nuclear export and translation of Yy2 mRNA in Snord17+/+ ISCs. The Yy2 protein subsequently binds the Tead4 promoter to promote its transcription, activating Hippo signaling, which is essential for ISC maintenance.
Peikang Zhang, Yuwei Xu, Yufei Lan, Zhen Xiong, Zhibin Yi, Runyuan Wu, Cunzhen Li, Ying Du, Hui Guo, Yingchi Yang, Zusen Fan   +10 more
wiley   +1 more source

Extracellular vesicles in colorectal cancer. [PDF]

Ann Coloproctol
Kim YI, Lee C, Lee H, Park IJ.
europepmc   +1 more source

The Activities of 1'-acetoxychavicol Acetate on SW620 Colorectal Cancer Cells Line

Pataweekorn Ketkomol, Thanapat Songsak, Suchada Jongrungruangchok, Apirada Sucontphunt, Fameera Madaka, Nalinee Pradubyat   +5 more
openalex   +2 more sources

Commentary: Low expression of SOD and PRX4 as indicators of poor prognosis and systemic inflammation in colorectal cancer [PDF]

Yan Zhang, Dong Xiao, Na Liu, Yonghong Li   +3 more
openalex   +1 more source

Targeting WEE1 in ARID1A/TP53 Concurrent Mutant Colorectal Cancer by Exploiting R‐Loop Accumulation and DNA Repair Deficiencies

Advanced Science, EarlyView.
ARID1A, a SWI/SNF complex component, is frequently mutated in colorectal cancer (CRC). CRC with ARID1A/TP53 concurrent mutations shows marked sensitivity to WEE1 inhibition. ARID1A loss induces R‐loop‐mediated replication stress, impairs ATF3 transcription, and amplifies WEE1i‐induced DNA damage, suggesting a promising therapeutic vulnerability ...
Chi Zhang, Yanjing Zhu, Luoyan Ai, Jingyuan Wang, Shan Yu, Yichen Wang, Xiaojing Xu, Mengling Liu, Yiyi Yu, Mengxuan Zhu, Yutong Liu, Zhenghang Xu, Haojie Zhou, Huishan Li, Qihong Huang, Qing Liu, Ke Peng, Tianshu Liu   +17 more
wiley   +1 more source

Targeting the ubiquitin-proteasome system and drug therapy in colorectal cancer. [PDF]

J Mol Cell Biol
Su R, Shao Y, Wang Q, Liu D, Wang Y, Kong D, Qiu Y.   +6 more
europepmc   +1 more source

Risk modeling of delayed postoperative bleeding after endoscopic submucosal dissection for early colorectal cancer and precancerous lesions

Jun Qian, Yali Tao, Shusen Zheng
openalex   +1 more source

Beyond Catalytic Therapy: Copper‐Paeonol Nanozymes Disrupt Fascin‐Mediated Actin Bundling to Suppress Tumor Growth and Metastasis

Advanced Science, EarlyView.
Copper‐paeonol nanozymes target tumor‐specific reactive oxygen species generation and disrupt fascin‐mediated actin bundling, effectively suppressing tumor growth and metastatic colonization. Abstract Fascin, an actin‐bundling protein universally upregulated in metastatic tumors, drives tumor migration and invasion by promoting filopodia and ...
Peiying Zhang, Huajun Li, Yisen Wang, Jie Xiang, Lei Fan, Shengzhe Zhang, Lizeng Gao, Hua Dai, Juqun Xi   +8 more
wiley   +1 more source

Social Burden and Healthcare Costs of Colorectal Cancer. [PDF]

Cancers (Basel)
Gąska I, Czerw A, Pajewska M, Partyka O, Deptała A, Badowska-Kozakiewicz A, Czerw N, Mękal D, Sygit K, Malikowska K, Drobnik J, Pobrotyn P, Waśko-Czopnik D, Sowiński T, Bandurska E, Ciećko W, Grochans E, Cybulska AM, Schneider-Matyka D, Rachubińska K, Iltchev P, Czapla T, Kozlowski R.   +22 more
europepmc   +1 more source