Results 261 to 270 of about 5,332,530 (372)
Lactylation‐Driven HECTD2 Limits the Response of Hepatocellular Carcinoma to Lenvatinib
Advanced Science, EarlyView.HECTD2 serves as an E3 ubiquitin ligase of KEAP1 to facilitate the antioxidative response and contributes to lenvatinib resistance in hepatocellular carcinoma. Lactylation of histone 3 on lysine residue 18 drives HECTD2 transcription. Targeting HECTD2 using PLGA‐PEG‐based nanoparticles offers novel strategies to overcome lenvatinib resistance in ...
Runyu Dong +12 more
wiley +1 more source
Clinical Characteristics, Management, and Outcomes of Colitis-Associated Colorectal Cancer and the Comparison With Sporadic Colorectal Cancer in Taiwan. [PDF]
Clin Transl GastroenterolWu HY +17 more
europepmc +1 more source
Serum copper concentration no help in diagnosis of colorectal cancer? [PDF]
, 1985 H Putzki, B Mlasowsky, Walter Düben
openalex +1 more source
Advanced Science, EarlyView.Targeting USP1 is identified as a strategy that significantly enhances type I IFN‐dependent innate immune response within the TME following radiotherapy. Mechanistically, USP1 inhibition facilitates STING trafficking from ER to Golgi by preserving K27‐linked oligo‐ubiquitination of SAR1A, thereby facilitating efficient activation of the dsDNA‐cGAS ...
Weilin Zhou +15 more
wiley +1 more source
Controlled trial of γ linolenic acid in Dukes's C colorectal cancer [PDF]
, 1987 Janet Treasure +2 more
openalex +1 more source
Advanced Science, EarlyView.Icaritin demonstrates broad antitumor effects by inhibiting colorectal cancer (CRC) cell proliferation, migration, invasion, and causing cell cycle arrest. It induces apoptosis by repressing autophagic flux through disrupting HSP90‐TXNDC9 interactions.
Dan He +6 more
wiley +1 more source
Colorectal Cancer: Pathogenesis and Targeted Therapy. [PDF]
MedComm (2020)Li J, Pan J, Wang L, Ji G, Dang Y.
europepmc +1 more source