Results 261 to 270 of about 5,919,627 (334)

ASCL2 drives colorectal cancer metastasis through transcriptional activation of TDGF1. [PDF]

Cell Oncol (Dordr)
Li D, Wang H, Yu Z, Zhang Y, Zhang J, Tao X, Wang F, Luo S, Lu Q.   +8 more
europepmc   +1 more source

Quality of life of colorectal cancer survivors in England: report on a national survey of colorectal cancer survivors using Patient Reported Outcome Measures (PROMs) [PDF]

, 2015
Corner, Jessica, Downing, Amy, Feltbower, Richard, Finan, Paul, Foster, Claire, Glaser, Adam W., Hunt, Katherine, Kind, Paul, Lawton, Sarah, Morris, Eva, Recio-Saucedo, Alejandra, Richards, Mike, Sebag-Montefiore, David, Simon, Michael, Thomas, James, Vernon, Sally, Wagland, Richard, Wood, Charlotte, Wright, Penny   +18 more
core   +1 more source

Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy

Advanced Science, EarlyView.
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu, Mengtao Sun, Lusheng Li, Jieqiong Wang, Shibiao Wan   +4 more
wiley   +1 more source

ERRATUM: Nutritional status and prognosis in metastatic colorectal cancer: a cohort study. [PDF]

Rev Assoc Med Bras (1992)
Soares Júnior JM.
europepmc   +1 more source

Tumor‐Derived Exosomal TAGLN2 Promotes Metastasis by Inducing Vascular Permeability and Angiogenesis via the NRP1/SEMA4D/YAP Axis

Advanced Science, EarlyView.
Gastric cancer‐derived exosomal TAGLN2 is identified as a key mediator of vascular reprogramming, with significantly elevated levels detected in patient serum. Independent of canonical SEMA4D signaling, it nucleates a cytoplasmic TAGLN2/NRP1/SEMA4D ternary complex that dually activates YAP, promoting angiogenesis, vascular dysfunction, and metastasis ...
Shuqi Yu, Jiajia Zhuo, Xiaoquan Hong, Shihao Rao, Yafang Ye, Dandan Kang, Huifang Peng, Huiqin Zhuo   +7 more
wiley   +1 more source

Sleep duration, selected circulating biomarkers, and colorectal cancer risk. [PDF]

Eur J Cancer Prev
Rossi M, Pauletto A, Mignozzi S, Bertuccio P, Tsilidis KK, Mutignani M, Cintolo M, Cottone I, Penagini R, Vecchi M, Katsoulis M, Rampelli S, D'Amico F, Corso G, Marino M, Rendine M, Del Bo' C, Riso P, Bonzi R, Guglielmetti S, La Vecchia C, Bravi F.   +21 more
europepmc   +1 more source

Enhancing CAR‐T Cell Efficacy in Solid Tumors by Inhibiting CCL5/VEGF‐Mediated Angiogenesis

Advanced Science, EarlyView.
This study reveals that CAR‐T cells in solid tumors produce CCL5, which paradoxically induces VEGF and angiogenesis to promote tumor growth. Blocking CCL5/VEGF signaling—through gene knockout, or the CCR5 inhibitor maraviroc—significantly enhances the antitumor efficacy of CAR‑T therapy (the diagram was created in Biorender).
Shishuo Sun, Qihong Li, Bixi Wang, Gang Wang, Ying Xue, Yibing Liang, Chenhe Hu, Zhenyu Wang, Xiaoge Gao, Haiheng Xu, Jun Song, Hailong Li, Liantao Li, Xiaoxiao Liu, Patrick Ming‐Kuen Tang, Qing Zhang   +15 more
wiley   +1 more source

Angiotensin‑converting enzyme 2 as an immune and prognostic biomarker in colorectal cancer. [PDF]

Sci Rep
Liu G, Yu X, Jiang W, He X, Nie H, Ou C.
europepmc   +1 more source

Epithelial TRIM27 Inhibits Intestinal Inflammation in Ulcerative Colitis by the USP7/TRIM27‐IKK Double Negative‐Feedback

Advanced Science, EarlyView.
ABSTRACT The E3 ubiquitin ligase tripartite motif 27 (TRIM27) is a negative regulator of NF‐κB activation and the innate immune response, and TRIM27 deficiency significantly impairs dextran sulfate sodium (DSS)‐induced colitis. The function of TRIM27 in intestinal epithelial cells (IECs), the mechanism by which TRIM27 inhibits the NF‐κB pathway and its
Weimin Xu, Zhebin Hua, Zhujiang Dai, Shasha Zhang, Yihan Jiang, Wensong Ge, YingWei Chen, Zhongchuan Wang, Bing Zhang, Chen‐Ying Liu, Peng Du   +10 more
wiley   +1 more source