Results 271 to 280 of about 5,332,530 (372)

Dissecting the Spatial and Single‐Cell Transcriptomic Architecture of Cancer Stem Cell Niche Driving Tumor Progression in Gastric Cancer

open access: yesAdvanced Science, EarlyView.
A single‐cell and spatial transcriptional atlas reveals the architecture of human gastric cancer stem cell (CSC) niche and the developmental trajectory of CSCs. These CSCs interact with immunosuppressive immune cells thereby constructing immune‐suppressive niche, and inflammatory cancer‐associated fibroblast (iCAFs) to enhance stemness through ...
Guangyu Zhang   +17 more
wiley   +1 more source

Neutrophil and Colorectal Cancer. [PDF]

open access: yesInt J Mol Sci
Masui H, Kawada K, Obama K.
europepmc   +1 more source

Squamocin Suppresses Tumor Growth through Triggering an Endoplasmic Reticulum Stress‐Associated Degradation of EZH2/MYC Axis

open access: yesAdvanced Science, EarlyView.
Squamocin disrupts mitochondrial respiratory Complex I function, reduces ATP production, and impairs HSP90α function, provoking endoplasmic reticulum (ER) stress and the unfolded protein response (UPR) in multiple cancer tumor models cell lines and in vivo tumor models.
Yin Zhu   +9 more
wiley   +1 more source

Language as a barrier to colorectal cancer screening in flanders: an ecological study. [PDF]

open access: yesArch Public Health
Van den Bergh S   +4 more
europepmc   +1 more source

Diet, faecal pH and colorectal cancer

open access: green, 1983
W. van Dokkum   +4 more
openalex   +1 more source

Hybrid EMT Phenotype and Cell Membrane Tension Promote Colorectal Cancer Resistance to Ferroptosis

open access: yesAdvanced Science, EarlyView.
Colorectal cancer cells (CRCs) cultured in 3D soft fibrin exhibit hybrid epithelial–mesenchymal transition (EMT) mediated ferroptosis resistance via WNT/β‐catenin signaling. Unlike 2D cells, 3D CRCs exhibit reduced E‐cadherin, knockout of which further enhances the defense against ferroptosis via adhesion‐mediated tension.
Xiaowei Wei   +12 more
wiley   +1 more source

Tumor‐Adhesive Chitosan‐Derived Multi‐Immune Agonist Unleashes Strong and Durable Anti‐Cancer Immunity

open access: yesAdvanced Science, EarlyView.
A tumor‐adhesive chitosan‐derived immune agonist TACTIC is developed for strong and durable anti‐tumor immunity. The immune agonist exhibits multi‐targets and modulates both tumor cell immunogenicity and pro‐inflammatory responses in immune cells, thereby potentiating the therapeutic efficacy of clinical radiotherapy.
Huilan He   +8 more
wiley   +1 more source

KIF3C inhibits the progression and proliferation of colorectal cancer. [PDF]

open access: yesBMC Gastroenterol
Diallo MT   +5 more
europepmc   +1 more source

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