Results 271 to 280 of about 5,289,946 (346)

Supplementary Table S4 from Elevated Resting Heart Rate Is an Independent Risk Factor for Mortality in Patients with Colorectal Cancer: A Retrospective Cohort Study

Wonhee Cho, Ho Seung Kim, Dong Hoon Lee, Dong‐Hyuk Park, Mi Kyung Lee, Seung Yoon Yang, Byung Soh Min, Kerry S. Courneya, Jeffrey A. Meyerhardt, E. Giovannucci, Nam Kyu Kim, Justin Y. Jeon   +11 more
openalex   +1 more source

Correction: An integrative analysis of transcriptome, methylome and single-cell RNA sequencing data identifies UBE2H as a marker of oxaliplatin resistance in colorectal cancer [PDF]

Jinman Fang, Qizhi Zhu, Bo Hong, Xueling Li, Hongzhi Wang   +4 more
openalex   +1 more source

NAD+‐Dependent Enzyme SIRT3 Limits Intestinal Epithelial Cell Functions Through NAD+ Synthesis Pathway in Colorectal Cancer

Advanced Science, EarlyView.
Microbiota‐derived quinolinic acid is used as an alternative source of replenishing the intracellular NAD+ pool induced by SIRT3 deficiency to regulate intestinal epithelial cell and T cell function, which has implications for targeting intestinal epithelial cells as an approach to the treatment of immune‐associated diseases, including colorectal ...
Ruiying Niu, Yingjie Dong, Jianghui Tong, Jingxuan Xia, Longhao Zhao, Zi Geng, Yingxin Lin, Jinghe Zhang, Xinyi Liu, Manqi Fang, Xi Jin, Yujing Bi, Guangwei Liu   +12 more
wiley   +1 more source

Accounting for Endoscopic Screening in Colorectal Cancer Risk Models. [PDF]

Cancer Epidemiol Biomarkers Prev
Wei EK, Wu K, Colditz GA, Giovannucci E, Chan AT, Song M, Rosner BA.   +6 more
europepmc   +1 more source

Spatial Profiling Reveals Distinct Molecular and Immune Evolution of Mouse Lung Adenocarcinoma Precancers with or Without Carcinogen Exposure

Advanced Science, EarlyView.
Tumor evolution in lung adenocarcinoma is shaped by genetic alterations and spatial immune dynamics. By integrating whole‐exome sequencing, imaging mass cytometry, and spatial transcriptomics across two mouse models, this study reveals how mutational burden, immune infiltration, and cell–state interactions evolve during early and late carcinogenesis ...
Bo Zhu, Muhammad Aminu, Pingjun Chen, Jian‐Rong Li, Chuanpeng Dong, Chenyang Li, Yanhua Tian, Shao‐Wei Lu, Hong Chen, Chenxi Ma, Xin Hu, Jie Ye, Andrew Y. Liu, Beibei Huang, Frank R. Rojas, Parra Cuentas. Edwin Roger, Ou Shi, Monique B. Nilsson, Alissa Poteete, Khaja B. Khan, Wei Lu, Luisa M. Solis Soto, Junya Fujimoto, Cara Haymaker, Ignacio I. Wistuba, Zhubo Wei, Linghua Wang, Don L. Gibbons, Ken Chen, Alexandre Reuben, Jason M. Schenkel, John V. Heymach, Chao Cheng, Jia Wu, Jianjun Zhang   +34 more
wiley   +1 more source

Colorectal cancer incidence, survival analysis and predictions (Monastir, Tunisia: 2002-2030). [PDF]

PLoS One
Bennasrallah C, Maatouk A, Kacem M, Dhouib W, Abroug H, Fredj MB, Safer L, Zaied S, Mokni M, Bouanène I, Belguith Sriha A, Zemni I.   +11 more
europepmc   +1 more source

An App-Based Behavioral Support Intervention Promoting Physical Activity (APPROACH) in Patients Diagnosed With Breast, Prostate, or Colorectal Cancer: Protocol for a Randomized Controlled Trial (Preprint)

Fiona Kennedy, Sue L Smith, Rebecca J. Beeken, Caroline Buck, Leanne Shearsmith, Hannah Truscott, Nicholas Counsell, Chloe Thomas, Anna Roberts, David Greenfield, Henry WW Potts, Nicholas Latimer, Ed Lowther, Lee Smith, Rosie Stevens, Amy Creaser, Jacqui Gath, Prof. Lynda Wyld, Abigail Fisher, Phillippa Lally   +19 more
openalex   +1 more source

PBRM1 Deficiency Reshapes an Immune Suppressive Microenvironment Through Epigenetic Tuning of PBRM1‐KDM5C‐IL6 Axis in ccRCC

Advanced Science, EarlyView.
PBRM1 ranks as the second most commonly mutated gene in ccRCC. This study reveals that PBRM1 loss promotes an immunosuppressive microenvironment by elevating M2 TAMs via the KDM5C–IL‐6 axis. These M2 TAMs, along with CAFs, form a barrier that excludes CD8+ T cells. Targeting IL‐6 synergizes with anti‐PD1 therapy, offering a promising strategy for PBRM1‐
Wenjiao Xia, Hongru Wang, Yu Dong, Zitong Yang, Yiyang Zhou, Zhinan Xia, Qinchen Li, Liangliang Ren, Yichun Zheng, Junliang Yan, Dongmei Ma, Zhi Chen, Xingang Cui, Guixin Zhu, Cheng Zhang   +14 more
wiley   +1 more source

The influence of periodontal disease and periodontal treatment on colorectal cancer. [PDF]

Radiol Oncol
Rebersak UP, Brecelj E, Schara R.
europepmc   +1 more source

TRIM38 Suppresses Breast Cancer Progression via Modulating SQSTM1 Ubiquitination and Autophagic Flux

Advanced Science, EarlyView.
TRIM38, an E3 ubiquitin ligase, suppresses breast cancer progression by inhibiting proliferation, migration, and invasion. Downregulated in breast tumor, its loss correlates with poor prognosis. Mechanistically, TRIM38 mediates K63‐linked ubiquitination of SQSTM1/p62 at K420, disrupting SQSTM1‐LC3 interaction and blocking autophagic flux.
Shan Jiang, Lijuan Wang, Dianwen Han, Peng Su, Bing Chen, Wenjing Zhao, Tong Chen, Ning Zhang, Xiaolong Wang, Yiran Liang, Yaming Li, Chen Li, Xi Chen, Dan Luo, Qifeng Yang   +14 more
wiley   +1 more source