Results 271 to 280 of about 5,673,125 (350)

PSMD14‐Mediated LDHA Deubiquitination Upregulates ACLY Expression via H3K18 Lactylation to Promote Lipid Synthesis and Pancreatic Cancer Progression

Advanced Science, EarlyView.
This study investigates the expression and functional role of the deubiquitinase PSMD14 in PC, with a focus on the mechanism by which it promotes lactate accumulation–induced histone lactylation, thereby driving aberrant lipid metabolism. These findings establish that dual targeting of PSMD14 and the glycolysis–lactylation signaling axis may represent ...
Ri‐Shang Lu, Li‐Kun Ren, Xiao‐Bin Fei, Song‐Bai Liu, Yong‐Jia Gao, Jun‐Yi Hou, Chi Wang, Peng Liu, Chang‐Hao Zhu, Xing Wang, Yao‐Zhen Pan   +10 more
wiley   +1 more source

Application of Patient Navigation in Colorectal Cancer Screening: A Scoping Review. [PDF]

Cancer Manag Res
Xia H, Wang J, Cheng C, Jiang Q, Guo T, Shen D, Geng H, Zhang T, Duan H.   +8 more
europepmc   +1 more source

Bifidobacterium longum suppresses colorectal cancer through the modulation of intestinal microbes and immune function [PDF]

Fangjian Shang, Xia Jiang, Haobo Wang, Shang Guo, Shuo Kang, Bin Xu, Xin Wang, Shihao Chen, Ning Li, Bo Liu, Zengren Zhao   +10 more
openalex   +1 more source

Targeting RBM10‐Repressed RORB Activity in Liquid Condensates Inhibits Lysosomal Biogenesis and Neuroblastoma Progression via Affecting NF‐κB Signaling

Advanced Science, EarlyView.
This study identifies that RBM10 represses the transcriptional activity of RORB in liquid condensates, resulting in down‐regulation of NR1D1 and RIOK3 that further activates NF‐κB activity to facilitate lysosomal biogenesis and aggressive features of NB cells.
Yanhua Guo, Xiaojing Wang, Chunhui Yang, Zhijie Wang, Xiaolin Wang, Xinyue Li, Jiaying Qu, Shunchen Zhou, Liduan Zheng, Qiangsong Tong   +9 more
wiley   +1 more source

Incidentalomas discoveries during staging and surveillance for colorectal cancer patients. [PDF]

Medicine (Baltimore)
Liu XR, Chen J, Zhang W, Liu Y, Peng D, Du DL.   +5 more
europepmc   +1 more source

WITHDRAWN: Prevalence and associations between gut bacteria with colorectal cancer: A study on colorectal cancer patients at Military Hospital 175, Vietnam

Vu Son Giang, Nguyễn Lĩnh Toàn, Ho Van Son, Dao Tien Manh, Nguyễn Thị Thân, Nguyen Lam Tung, Nguyen Cam Thach, Le Huu Cuong   +7 more
openalex   +1 more source

Lactate Activates the HCAR1/β‐Arrestin2/PP2A Signaling Axis to Mediate STAT1/2 Dephosphorylation and Drive Osteosarcoma Progression

Advanced Science, EarlyView.
In the present study, it is found that in osteosarcoma, lactate‐activated HCAR1 promotes β‐arrestin 2 translocation from cytoplasm to nucleus. In the nucleus, β‐arrestin 2 recruits PP2A to the activated STAT1/2 dimers, mediating STAT1/2 dephosphorylation and inhibiting the transcription of downstream anti‐oncogenes to promote OS progression.
Zhitao Han, Qi Jia, Guangjian Bai, Zhao Li, Jin Zeng, Zhenhua Wang, Jing Zhang, Jiashi Cao, Baoquan Xin, Yonggang Liu, Jingyu Shen, Lining Wang, Xing Huang, Chunlei Zhang, Kai Tong, Fenglei Dai, Yajie Zhang, Weina Zhu, Songyi Cheng, Yuanming Chen, Xinghai Yang, Guanghui Chen, Zhenhua Zhou, Yong Ma, Weibo Liu, Ting Wang, Tielong Liu   +26 more
wiley   +1 more source

Factors affecting survival in patients with colorectal cancer: an umbrella review. [PDF]

J Transl Med
Yu L, Yuan J, Lou S, Huang A, Cai X, Ji J, Dai X, Mao X, Mao Y, Sun L.   +9 more
europepmc   +1 more source

Colorectal Cancer Screening among Underserved Korean Americans in Los Angeles County

, 2007
Angela M. Jo, Annette E. Maxwell, Weng Kee Wong, Roshan Bastani   +3 more
openalex   +1 more source