Results 291 to 300 of about 5,289,946 (346)

Quality of Life of Colorectal Cancer Patients Treated with Chemotherapy. [PDF]

Nutrients
Ziętarska M, Małgorzewicz S.
europepmc   +1 more source

IL4I1⁺ Macrophages and TDO2⁺ Myofibroblasts Drive AhR‐Mediated Immunosuppression and Ferroptosis Resistance in Solid Predominant Lung Adenocarcinoma

Advanced Science, EarlyView.
Solid predominant lung adenocarcinoma exhibits an immune‐excluded, ferroptosis‐resistant niche enriched with IL4I1⁺ TAMs and TDO2⁺ myCAFs. Spatial and multi‐omics analyses reveal AhR‐driven crosstalk that promotes T cell exhaustion and therapy resistance. Blocking AhR with CH‐223191 restores ferroptosis sensitivity, and its combination with ferroptosis
Zhaoxuan Wang, Weijiao Xu, Lei Zhao, Lin Zhong, Wendan Yu, Shengmin Wang, Lu Sun, Tao Guo, Fengzhou Li, Zhuoshi Li, Lei Fang, Shiqing Wang, Guohui Zhang, Guoqing Xue, Wei Guo, Shilei Zhao, Chundong Gu   +16 more
wiley   +1 more source

Full BLOOD count TRends for colorectal cAnCer deteCtion (BLOODTRACC): external validation of colorectal cancer prediction models in English primary care

Virdee PS, Birks J, Holt T, Snell KI, Abel G, Nicholson BD.   +5 more
europepmc   +1 more source

SREBP2 confers ferroptosis resistance by targeting GPX4 in colorectal cancer. [PDF]

Apoptosis
Zhong H, Chen R, Chen T, Lin M, Wen S, Zhang M, Liu D, Yu J, Chen J, Yi B, Liang R, Jiang W, Li Z.   +12 more
europepmc   +1 more source

The KDM6B/SLC10A2 Axis Suppresses MDSCs Recruitment via ERK/AP‐1 Signaling in Colorectal Cancer

Advanced Science, EarlyView.
In wild‐type intestinal epithelial cells, KDM6B demethylates SLC10A2 to promote its expression, after which SLC10A2 suppresses ERK phosphorylation, inhibiting AP‐1 (Fos/Jun) transcription and chemokine production. In KDM6B‐deficient intestinal epithelial cells, SLC10A2 methylation increases, and its expression decreases.
Zhibo Hu, Jing Xun, Bin Liu, Xiaolin Jiang, Yingdi Han, Huichao Yang, Qi Gao, Ruifang Gao, Aimin Zhang, Xueliang Wu, Dapeng Zhang, Dihua Li, Tian Li, Shimin Yang, Ximo Wang, Xiangyang Yu, Qi Zhang   +16 more
wiley   +1 more source

Five-Year Experience of Nationwide Implementation of Colorectal Cancer Screening in Sweden. [PDF]

United European Gastroenterol J
Hreinsson JP, Pischel A, Pålsson B, National Working Group for Colorectal Cancer Screening in Sweden (NWGCRCSS), Blom J.   +4 more
europepmc   +1 more source

Diagnostic value of multi-gene methylation in colorectal cancer screening. [PDF]

Front Oncol
Yang Q, Chen L.
europepmc   +1 more source

EnteroMix and the emerging role of MRNA-based therapeutics in colorectal cancer: from preclinical tumor regression to clinical translation

Mohamad Khalil, Muhammad Hassan, Mahnoor Fatima, Muhammad Talha, Omar Abdullah Gill   +4 more
openalex   +1 more source

Expression and Clinical Significance of CD47 in Colorectal Cancer: A Review. [PDF]

Cancers (Basel)
Li Q, Vignali P, Tang D, Martinelli G, Fuochi B, Sparavelli R, Poma AM, Bruno R, Macerola E, Ugolini C.   +9 more
europepmc   +1 more source