Results 111 to 120 of about 789,387 (385)
Increased lymph node yield in colorectal cancer is not necessarily associated with a greater number of lymph node positive cancers [PDF]
, 2014 Peer reviewedPublisher ...
Aly, Omar +5 more
core +2 more sources
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Cancer, 2018 In 2016, the Microsimulation Screening Analysis‐Colon (MISCAN‐Colon) model was used to inform the US Preventive Services Task Force colorectal cancer (CRC) screening guidelines.
Elisabeth F P Peterse +8 more
semanticscholar +1 more source
, 2007 Adenomatous polyps are the known precursors of the majority of colorectal cancers, with the risk of malignancy increasing with increasing polyp size.
Vassallo, Pierre
core
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
Molecular Oncology, EarlyView.The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source
Inquiry: The Journal of Health Care Organization, Provision, and Financing, 2019 Implementation of population-based colorectal cancer screening programs by Medicaid health plans could address colorectal cancer screening disparities.
Elizabeth Witwer MPH +2 more
doaj +1 more source
Colonoscopy: the current king of the hill in the United States [PDF]
, 2014 Colonoscopy is the dominant colorectal cancer screening strategy in the USA. There are no randomized controlled trials completed of screening colonoscopy, but multiple lines of evidence establish that colonoscopy reduces colorectal cancer incidence in ...
Rex, Douglas K.
core +1 more source
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Colorectal cancer screening: An updated review of the available options
World Journal of Gastroenterology, 2017 Colorectal cancer (CRC) is a significant cause of morbidity and mortality worldwide. However, colon cancer incidence and mortality is declining over the past decade owing to adoption of effective screening programs.
I. Issa, Malak S. Noureddine
semanticscholar +1 more source
Population-based colorectal cancer screening by colonoscopy or CT colonography [PDF]
, 2013 In 1968 at request of the World Health Organization (WHO), Wilson and Jungner defined 10 criteria for informed population-based screening.(1) In subsequent years, these criteria have been reevaluated and revised several times.
Stoop, E.M. (Esther)
core