Results 151 to 160 of about 4,110,582 (295)

Bifidobacterium Pseudolongum‐Derived Inosine Mitigates Polystyrene Nanoplastics‐Induced Hepatic Injury by Inhibiting the Polarization of M1 Macrophages

Advanced Science, EarlyView.
Probiotic B.p colonization elevated gut‐derived inosine level in the liver, while elevated inosine activated A2AR and subsequently blocked NPs‐induced polarization of M1 macrophages by repressing the miR155/SOCS1/NF‐κB pathway. This reduced the release of inflammatory cytokines and thereby, mitigated NPs‐induced hepatic injury.
Kaikai Zhang, Yuchuan Chen, Jiayuan Wan, Jianzheng Yang, Lijian Chen, Qingyuan Li, Anding Zhou, Nian Zhou, Jiuyang Ding, Qi Wang, Jian Sun   +10 more
wiley   +1 more source

Evaluation of Pilot Colorectal Cancer Screening Programs in Iran

مجله اپیدمیولوژی ایران, 2016
Background and Objectives: Colorectal cancer is the third most common cancer in men and the second most common cancer in women in the world. The colorectal cancer screening program was conducted in Iran as a pilot in the late 2010 with the aim of ...
H Mirzaei, MH Panahi, K Etemad, A GHanbari-Motlagh, K Holakouie-Naini   +4 more
doaj  

Here are some early symptoms of colorectal cancer [PDF]

That\ue2\u20ac\u2122s right, there aren\ue2\u20ac\u2122t any.Colorectal cancer starts with NO SYMPTOMS. That's why screening tests are important, especially if you\ue2\u20ac\u2122re over 50. Colorectal cancer is the 2ND LEADING CANCER KILLER in the U.S.,

core  

Loss of E3 Ubiquitin Ligase RINES via CpG Methylation Relieves Suppression of STAT3 and MYC, Facilitating Multiple Tumorigeneses

Advanced Science, EarlyView.
Dysregulated protein modifications drive tumorigenesis. RINES, an E3 ubiquitin ligase, represses tumor cell proliferation and metastasis by facilitating RING domain‐dependent, ubiquitin–proteasome‐mediated degradation of STAT3 and MYC, which consequently restrains cancer stemness and oncogenic progression.
Lili Li, Ka Man Ng, Xingsheng Shu, Xiaoxue Chai, Kai Yau Wong, Gopesh Srivastava, Anthony T.C. Chan, Wai Yee Chan, Qian Tao   +8 more
wiley   +1 more source

A Simpler Draw: Rethinking Colorectal Cancer Screening for Adults With Intellectual and Developmental Disabilities. [PDF]

Cureus
Todd A, Modi R, Jacob R.
europepmc   +1 more source

National Cancer Screening Service Annual Report 2007-2008

, 2008
The first annual report of the National Cancer Screening Service Board (NCSSB) which was established on 01 January ...
National Cancer Screening Service
core  

Selenium Nanoparticles Selectively Target KRAS G13D to Inhibit Colorectal Cancer

Advanced Science, EarlyView.
The mechanisms of SeNPs therapy in cancer treatment, encompass three parallel actions: (1) seleno‐amino acids, key metabolites, upregulate GPX2 expression, thereby inhibiting tumor metastasis via the GPX2‐HIF1α‐VEGF signaling pathway; (2) selenite (SeO32−), an inorganic metabolite, forms hydrogen bonds with amino acid residues 13–17 of the KRAS G13D ...
Xiaoting Liu, Chong Wu, Shiyao Song, Li Ma, Shaoqing Huang, Yuting He, Qinghai Li, Yanzhou Chang, Dan Jiang, Yong Mei, Junchao Cai, Zhenshuang Du, Tianfeng Chen, Weiling He   +13 more
wiley   +1 more source

Colorectal cancer screening in individuals with multiple sclerosis: A mixed-methods study. [PDF]

Mult Scler
Pierret C, Bouvier R, Kerbrat S, Leray E.   +3 more
europepmc   +1 more source

National Cancer Screening Service Annual Financial Statements 2007

, 2008
Audited financial statements of the National Cancer Screening Service Board for the year ended 31 December ...
National Cancer Screening Service
core  

ANXA2+ Small Extracellular Vesicles Drive Chemoresistance in Anaplastic Thyroid Cancer by Promoting XRCC5 Lactylation and Enhancing Non‐Homologous End‐Joining Repair

Advanced Science, EarlyView.
ANXA2+ sEVs promote cisplatin resistance in ATC by stabilizing the SRC/LDHA interaction, increasing LDHA phosphorylation and activity, and lactate production. Elevated lactate levels promote KAT5‐mediated lactylation of XRCC5 at lysine 265, enhancing its binding to XRCC6.
Shanshan Su, YiShan Xiong, Yuxuan Liang, Xiang Min, Daofeng Dai   +4 more
wiley   +1 more source