Acromegaly and Colorectal Neoplasm: An Update. [PDF]
Acromegaly is a systemic disease caused by excessive inappropriate secretion of GH and IGF-I levels, resulting in many systemic complications, including cardiovascular, respiratory, metabolic diseases, and a possible increased risk of some neoplasias ...
Kasuki L, Maia B, Gadelha MR.
europepmc +6 more sources
Risk Factors Associated With Early-Onset Colorectal Neoplasm in Chinese Youth: A Prospective Population-Based Study. [PDF]
Evidence of the risk factors associated with early-onset colorectal neoplasm from prospective population-based studies is limited. We enrolled 17,293 participants younger than 50 years from the Shanghai colorectal cancer (CRC) screening program cohort ...
Shen J+7 more
europepmc +4 more sources
Implications of Lifestyle Factors and Polygenic Risk Score for Absolute Risk Prediction of Colorectal Neoplasm and Risk-Adapted Screening. [PDF]
Background: Estimation of absolute risk of developing colorectal neoplasm is essential for personalized colorectal cancer (CRC) screening. We developed models to determine relative and absolute risks of colorectal neoplasm based on lifestyle and genetic ...
Chen H+10 more
europepmc +4 more sources
Analysis of Syndecan-2 Methylation in Bowel Lavage Fluid for the Detection of Colorectal Neoplasm. [PDF]
Background/Aims Syndecan-2 (SDC2) methylation was previously reported as a sensitive serologic biomarker for the early detection of colorectal cancer (CRC).
Park YS+11 more
europepmc +4 more sources
Development and validation of a scoring system for advanced colorectal neoplasm in young Korean subjects less than age 50 years. [PDF]
Background/Aims Colorectal cancer incidence among patients aged ≤50 years is increasing. This study aimed to develop and validate an advanced colorectal neoplasm (ACRN) screening model for young adults aged
Kim JY+12 more
europepmc +4 more sources
Factors influencing advanced colorectal neoplasm anatomic site distribution in China: An epidemiological study based on colorectal cancer screening data. [PDF]
Existing studies indicate that advanced colorectal neoplasms exhibit distinct clinical and biological traits based on anatomical sites. However, in China, especially for advanced colorectal neoplasms, there's limited information available on these traits.
Zhao K+13 more
europepmc +2 more sources
Association between the severity of metabolic dysfunction-associated fatty liver disease and the risk of colorectal neoplasm: a systematic review and meta-analysis. [PDF]
Background The severity of metabolic dysfunction-associated fatty liver disease (MAFLD) reportedly plays a part in the etiology of colorectal tumors. However, there is no consensus.
Zeng Y, Cao R, Tao Z, Gao Y.
europepmc +2 more sources
Prediction of the histology of colorectal neoplasm in white light colonoscopic images using deep learning algorithms. [PDF]
The treatment plan of colorectal neoplasm differs based on histology. Although new endoscopic imaging systems have been developed, there are clear diagnostic thresholds and requirements in using them.
Choi SJ, Kim ES, Choi K.
europepmc +2 more sources
Fecal microbial DNA markers serve for screening colorectal neoplasm in asymptomatic subjects. [PDF]
We have previously shown that fecal microbial markers might be useful for non‐invasive diagnosis of colorectal cancer (CRC) and adenoma. Here, we assessed the application of microbial DNA markers, as compared with and in combination with fecal ...
Liang JQ+8 more
europepmc +2 more sources
The role of microvesicles as biomarkers in the screening of colorectal neoplasm. [PDF]
AbstractBackgroundColorectal cancer (CRC) is the second cause of cancer death worldwide. The role of circulating microvesicles as a screening tool is a novel, yet effective approach that warrants prioritised research.MethodsIn a two‐gate diagnostic accuracy study, 35 patients with benign colorectal polyps (BCRP) (n = 16) and colorectal cancer (CRC) (n =
Eddama MMR+6 more
europepmc +5 more sources