Results 41 to 50 of about 638,404 (291)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Socio-Demographic Characteristics of Study Subjects by Colorectal Neoplasm Staging.
, 2013 Note: AJCC = American Joint Committee on Cancer*Significant difference between colorectal neoplasm staging (except unknown stage)by One-Way ANOVA†Significant difference between colorectal neoplasm staging (except unknown stage)by Chi-square Test ...
Dora L. W. Kwong (166235) +3 more
core +1 more source
Increased prevalence of colorectal adenomas in women with breast cancer [PDF]
, 2005 Background: The frequency of colorectal adenomas and carcinomas was investigated in a large cohort of women with breast cancer in comparison with matched controls, since data on the occurrence of second tumors in women with breast cancer is controversial.
Späth, Lydia +9 more
core +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Infiltration of plasma cells in colorectal adenocarcinoma associated with autoimmune encephalitis
Annals of Clinical and Translational Neurology, 2021 Paraneoplastic autoimmune encephalitis (PAE) represents a group of rare neurological syndromes associated with neoplastic diseases. Here, we report a case that multiple anti‐neuronal antibodies were present in a patient with PAE who developed both small ...
Yaqing Shu +9 more
doaj +1 more source
Clinical Characteristics of Study Subjects by Colorectal Neoplasm Staging.
, 2013 Note: AJCC = American Joint Committee on Cancer*Other included those who had unknown or double primary site.†Significant difference between colorectal neoplasm staging (except unknown stage) by One-Way ANOVA‡Significant difference between colorectal ...
Dora L. W. Kwong (166235) +3 more
core +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Indonesian Journal of Cancer, 2014 Colorectal cancer is a rare yet aggressive neoplasm in young adult. This cancer was associated with several bacterial and viral infections like Streptococcus bovis, Helicobacter pylori, human papilloma virus, and Clostridium septicum.
NATA PRATAMA HARDJO LUGITO +2 more
doaj +1 more source
Infection and Colorectal Neoplasm
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy, 2015 Colorectal cancer is a major cause of cancer-related morbidity and mortality. Colorectal cancer is the third most common malignancy and the 4th most common cause of cancer mortality worldwide. A number of infectious agents are considered to be cancer risk factors due to the hypothesis-generating and supportive evidence accumulated to date.
Gontar Alamsyah Siregar +2 more
openaire +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source