Results 101 to 110 of about 332,251 (304)

The role of microvesicles as biomarkers in the screening of colorectal neoplasm. [PDF]

Cancer Med, 2022
Eddama MMR, Gurung R, Fragkos K, Lorgelly P, Cohen R, Loizidou M, Clapp L.   +6 more
europepmc   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Clinical Practice of Endoscopic Submucosal Dissection for Early Colorectal Neoplasms by a Colonoscopist with Limited Gastric Experience

Gastroenterology Research and Practice, 2013
Objectives. Endoscopic submucosal dissection (ESD) for early colorectal neoplasms is regarded as a difficult technique and should commence after receiving the experiences of ESD in the stomach.
Wen-Hsin Hsu, Meng-Shun Sun, Hoi-Wan Lo, Ching-Yang Tsai, Yu-Jou Tsai   +4 more
doaj   +1 more source

Effectiveness and Safety of Endoscopic Submucosal Dissection for Colorectal Neoplasm in Patients with High Charlson Comorbidity Index Score: A HASID Multicenter Study. [PDF]

J Clin Med, 2023
Kim DH, Jung YW, Jin BC, Oh HH, Song HY, Kim SJ, Myung DS, Kim SW, Lee J, Seo GS, Joo YE, Kim HS.   +11 more
europepmc   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

Malakoplakia mimicking a locally advanced colorectal neoplasm. [PDF]

J Surg Case Rep, 2021
Irarrázaval-Mainguyague MJ, Cabreras M, Oksenberg S, Pulgar MA, Rojas F, Álvarez M, Quezada-Diaz FF.   +6 more
europepmc   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

Application of Artificial Intelligence in the Detection and Characterization of Colorectal Neoplasm. [PDF]

Gut Liver, 2021
Kim KO, Kim EY.
europepmc   +1 more source

Sa1587 Is the Prevalence of Colorectal Adenoma Higher in Patients With Gastric Neoplasm? [PDF]

, 2011
Chang Hwan Choi, Sang Pyo Han, Bong Ki, Beom Jin Kim, Hyoung‐Chul Oh, Jeong Wook Kim, Jae Hyuk, Jae Gyu Kim, Se Kyung Chang   +8 more
openalex   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source