Heterogeneity in the Relationship between Disinfection By-Products in Drinking Water and Cancer: A Systematic Review. [PDF]
, 2018 The epidemiological evidence demonstrating the effect of disinfection by-products (DBPs) from drinking water on colon and rectal cancers is well documented.
Benmarhnia, Tarik +4 more
core +2 more sources
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Current Status of Chemotherapy in Colorectal Cancer: Updated Treatment Strategies
The Korean Journal of GastroenterologyColorectal cancer remains a significant health burden in South Korea, being the third most diagnosed cancer in the country. Despite advances in treatment, patients with metastatic colorectal cancer still face limited survival rates, with resection often ...
Jae Hyun Kim, Seun Ja Park
doaj +1 more source
World Journal of Surgical Oncology, 2019 Background Post-treatment management is essential for improving the health and quality of life of colorectal cancer (CRC) survivors. The number of cancer survivors is continually increasing, which is causing a corresponding growth in the need for ...
Ameera Balhareth +2 more
doaj +1 more source
UCN-01 enhances cytotoxicity of irinotecan in colorectal cancer stem-like cells by impairing DNA damage response [PDF]
, 2016 Colorectal cancer (CRC) is one of the most common and lethal cancers worldwide. Despite recent progress, the prognosis of advanced stage CRC remains poor, mainly because of cancer recurrence and metastasis.
Biffoni, Mauro +9 more
core +1 more source
Molecular Oncology, EarlyView.Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor +2 more
wiley +1 more source
Expression of Ciclooxigenase-2 in colorectal carcinoma, a narrative review
Iatreia, 2019 The development of colorectal carcinoma is a sequential process associated to chromosomic instability and to mutations of oncogenes as KRAS, of tumor suppressor gene as p53, or loss of APC, leading to uncontrolled cell proliferation and transformation ...
Benedetti Padrón, Inés +1 more
doaj +1 more source
The changing face of cancer therapeutics improved : outcome and decreased toxicity with Molecular Targeted Drugs [PDF]
, 2004 The treatment of patients with cancer has largely involved the administration of cytotoxic drugs with narrow therapeutic indices, with little selectivity for cancer cells over normal proliferating cells.
Attard, Gerhardt, De Bono, Johann S.
core
Cancer in Ancient Human Populations: Methods and Practice in Bioarchaeology and Paleopathology [PDF]
, 2020 Best Undergraduate Writing in Anthropology Award, 2019-2020Despite its prevalence in contemporary public health, research on the paleopathology of cancer is still extremely limited.
Gardner, Elijah
core
Laparoscopic left lateral segmentectomy for metachronic metastases of small intestine adenocarcinoma: a case report [PDF]
, 2011 Hepatectomy has been the standard treatment for metachronic metastases of non-colorectal (NCR) origin, mainly when the disease-free interval is more than two years.
Araujo, Sergio Luiz Melo +4 more
core +4 more sources