Results 71 to 80 of about 638,404 (291)

Anticipated regret to increase uptake of colorectal cancer screening (ARTICS):a randomised controlled trial [PDF]

, 2015
Screening is important for early detection of colorectal cancer. Our aim was to determine whether a simple anticipated regret (AR) intervention could increase uptake of colorectal cancer screening. A randomised controlled trial of a simple, questionnaire-
Brownlee, Linda A., Steele, Robert J. C., O'Carroll, Ronan E., Steele, Robert, Chambers, Julie A., Chambers, Julie, Brownlee, Linda, Libby, Gillian, Steele, Robert J.C., O'Carroll, Ronan   +9 more
core   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Screen for Life: National Colorectal Cancer Action Campaign 2012 year end report [PDF]

The Centers for Disease Control and Prevention\u2019s (CDC) Screen for Life: National Colorectal Cancer Action Campaign (SFL) is a multiyear, multimedia initiative to educate men and women aged 50 years and older\u2014the age group at greatest risk of ...

core   +2 more sources

Thirty-day postoperative mortality after colorectal cancer surgery in England. [PDF]

, 2011
OBJECTIVES: To assess the variation in risk-adjusted 30-day postoperative mortality for patients with colorectal cancer between hospital trusts within the English NHS.
Quirke, Philip, Finan, Paul J, B. Rachet, E. F. Taylor, D. Forman, E. J. A. Morris, P. J. Finan, Thomas, James D, M. P. Coleman, Taylor, Elizabeth F, Forman, David, J. D. Thomas, Coleman, Michel P, P. Quirke, Rachet, Bernard, Morris, Eva JA   +15 more
core   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Review of economic evidence in the prevention and early detection of colorectal cancer. [PDF]

, 2013
This paper aims to systematically review the cost-effectiveness evidence, and to provide a critical appraisal of the methods used in the model-based economic evaluation of CRC screening and subsequent surveillance.
Kim E Jeong, Cairns, John A, Jeong, Kim E., John A Cairns, Jeong, Kim E, Cairns, John A.   +5 more
core   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Asymptomatic Colonic Anisakiasis: Is It So Rare?

Case Reports in Gastroenterology, 2020
Most cases of anisakiasis occur in the stomach. Colonic anisakiasis, especially when asymptomatic, is extremely rare. We report a case of asymptomatic colonic anisakiasis and present a literature review of cases of colonic anisakiasis.
Tetsuro Takasaki, Toru Yamada, Junji Kinoshita, Yasuaki Motomura   +3 more
doaj   +1 more source

GSTP1 and GSTA1 polymorphisms interact with cruciferous vegetable intake in colorectal adenoma risk.

, 2005
The possible interplay between cruciferous vegetable consumption, functional genetic variations in glutathione S-transferases (GST) M1, T1, P1, and A1, and colorectal adenomas, was investigated in a Dutch case-control study.
Nagengast, Fokko M, Visker, Marleen H P W, Aarts, Jac M M J G, Kampman, Ellen, Visker, Marleen HPW, Nagengast, Fokko M., Kok, Frans J., Tijhuis, Mariken J, Wark, Petra A, Wark, Petra A.; id_orcid, Tijhuis, Mariken J., Aarts, Jac MMJG, Kok, Frans J, Wark, P.A., Kok, F.J., Tijhuis, M.J., Visker, M.H.P.W., Aarts, J.M.M.J.G., Kampman, E., Nagengast, F.M., Aarts, J.   +20 more
core   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source