Results 1 to 10 of about 9,868 (158)
Three synchronous primary carcinomas in a patient with HNPCC associated with a novel germline mutation in
World Journal of Surgical Oncology, 2009 Background MLH1 is one of six known genes responsible for DNA mismatch repair (MMR), whose inactivation leads to HNPCC. It is important to develop genotype-phenotype correlations for HNPCC, as is being done for other hereditary cancer syndromes, in order
Yee Herman +6 more
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The difficult diagnosis of a patient presenting with a Krukenberg tumor and Lynch syndrome: a case report [PDF]
Journal of Medical Case ReportsBackground Krukenberg tumors are a rare condition representing only 1% of ovarian tumors. Lynch syndrome only results in ovarian tumors in 1% of cases. Both diagnoses can be challenging, leading to delayed treatment.
Amaury Poque +2 more
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Anais Brasileiros de Dermatologia, 2015 Muir-Torre syndrome is a rare genodermatosis characterized by the occurrence of at least one sebaceous tumor associated with visceral neoplasia, but with no predisposing factors.
Catharina Maria Freire de Lucena Pousa +4 more
doaj +1 more source
Lynch syndrome: An unusal case of familial cancer unearthed
Indian Journal of Pathology and Microbiology, 2022 Lynch syndrome or hereditary nonpolyposis colorectal cancer (HNPCC) is a type of inherited cancer syndrome with a genetic predisposition to different types of cancer.
Subhra Dhar +4 more
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Hereditary colorectal cancer syndromes [PDF]
Iranian Journal of Colorectal Research, 2020 Context: In recent decades there has been an increase in hereditary colorectal cancer cases in people under 50 years of age. Several studies revealed similar pathologies with both molecular and clinical variations about hereditary colorectal neoplasms ...
Fernanda Rivera +2 more
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International Journal of Nursing Sciences, 2023 Objectives: This study aimed to investigate colorectal cancer-related knowledge, health beliefs, and screening behaviour in first-degree relatives (FDRs) of patients with Lynch syndrome-associated colorectal cancer (CRC) and explore the predictive ...
Jiaojiao Gu +4 more
doaj +1 more source
Prevalence of Lynch Syndrome among Patients with Newly Diagnosed Endometrial Cancers [PDF]
, 2013 Background: Lynch syndrome (LS) is a hereditary condition that increases the risk for endometrial and other cancers. The identification of endometrial cancer (EC) patients with LS has the potential to influence life-saving interventions.
Alenda, Cristina +17 more
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Cancer Medicine, 2023 Background Persons with hereditary cancer syndromes (carriers) have a higher risk of developing cancer early. They are confronted with decisions regarding prophylactic surgeries, communication within their families, and childbearing.
Anna Maria Kastner +4 more
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Muir-Torre Syndrome: The Importance of a Detailed Family History
Case Reports in Ophthalmology, 2019 Muir-Torre syndrome, a variant of Lynch syndrome or hereditary nonpolyposis colorectal cancer, is an autosomal dominant disease characterized by skin neoplasms (sebaceous or keratoacanthomas) and visceral malignancies.
Christopher K.H. Burris +7 more
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Journal of Coloproctology, 2020 Introduction: Colorectal carcinoma is the third most prevalent neoplasm in the world, and the second cause of death by cancer. The most part of these neoplasms are sporadic by somatic mutations, but around 15% are hereditary, such as Lynch syndrome or ...
Maria Beatriz de Matos +2 more
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