Results 81 to 90 of about 809,703 (372)

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

Molecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld, Stefan Kühberger, Ricarda Graf, Christine Beichler, Markus Braun, Nadia Dandachi, Ellen Heitzer, Gerald W. Prager   +7 more
wiley   +1 more source

A Hierarchical Transformer Encoder to Improve Entire Neoplasm Segmentation on Whole Slide Image of Hepatocellular Carcinoma [PDF]

arXiv, 2023
In digital histopathology, entire neoplasm segmentation on Whole Slide Image (WSI) of Hepatocellular Carcinoma (HCC) plays an important role, especially as a preprocessing filter to automatically exclude healthy tissue, in histological molecular correlations mining and other downstream histopathological tasks.
arxiv  

A Risk-Scoring System Combined With a Fecal Immunochemical Test Is Effective in Screening High-Risk Subjects for Early Colonoscopy to Detect Advanced Colorectal Neoplasms.

Gastroenterology, 2016
BACKGROUND & AIMS Age, sex, smoking, and family history are risk factors for colorectal cancer in Asia. The Asia-Pacific Colorectal Screening (APCS) scoring system was developed to identify subjects with a high risk for advanced neoplasm (AN).
Han-Mo Chiu, J. Ching, Kai‐chun Wu, R. Rerknimitr, Jingnan Li, Deng-Chiang Wu, K. Goh, T. Matsuda, Hyunsoo Kim, Rupert Leong, K. Yeoh, V. Chong, J. Sollano, F. Ahmed, Jayaram Menon, J. Sung   +15 more
semanticscholar   +1 more source

Novel Method for Screening Colorectal Neoplasm

EBioMedicine, 2015
Colorectal cancer (CRC) is one of the leading causes of cancer death worldwide with the majority of cases having no previous family history. The most effective way to reduce mortality is to detect precancerous adenoma in an early stage. Several screening methods are now available; however as each modality has its limitation there is no superb strategy ...
openaire   +4 more sources

Clinicopathological hallmarks and biomarkers of colorectal neuroendocrine neoplasms

PLOS ONE, 2017
Chromogranin A (CgA) is a well-established marker for diagnosis and follow up of patients with gastroenteropancreatic neuroendocrine neoplasms (GEP-NEN). Recently, it has been shown that plasma levels of CgA correlate with tumor load and predict survival of patients with NEN of the small bowel.
Sebastian Krug, Sebastian Krug, Patrick Michl, Philipp Stroebel, Peter H. Kann, Michael Scharf, Volker Ellenrieder, Alexander Koenig, Alexander Koenig, Thomas M. Gress, Peter Barth, Peter Barth, Anja Rinke, Daniela Mueller, Kia Homayunfar, Roland Moll, Ute Koenig   +16 more
openaire   +6 more sources

Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance

Molecular Oncology, EarlyView.
In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang, Haimei Wen, Ying Chen, Jingya Ning, Di Hu, Yujiao Dong, Chenyu Yao, Bo Yuan, Shuanying Yang   +8 more
wiley   +1 more source

The PTTG1/VASP axis promotes oral squamous cell carcinoma metastasis by modulating focal adhesion and actin filaments

Molecular Oncology, EarlyView.
VASP was found to be overexpressed in metastatic oral squamous cell carcinoma (OSCC) tissues. Notably, PTTG1‐ and VASP‐deficient OSCC cells demonstrated suppressed metastatic properties by disrupting the interaction between the cytoskeleton and focal adhesion (FAs) in the filopodia region.
Suyeon Park, Sang Shin Lee, Shihyun Kim, Yeonjun Lee, Gyeonwon Park, Jung Oh Kim, Jongho Choi   +6 more
wiley   +1 more source

Presence of Iron in Colorectal Adenomas and Adenocarcinomas

Gut and Liver, 2008
Background/Aims: Iron overload reportedly increases the risk of colorectal neoplasms, but the distribution of tissue iron in a colorectal neoplasm remains controversial.
doaj   +1 more source

Efficacy of capillary pattern type IIIA/IIIB by magnifying narrow band imaging for estimating depth of invasion of early colorectal neoplasms

BMC Gastroenterology, 2010
Background Capillary patterns (CP) observed by magnifying Narrow Band Imaging (NBI) are useful for differentiating non-adenomatous from adenomatous colorectal polyps.
Fu Kuang-I, Uraoka Toshio, Saito Yutaka, Emura Fabian, Matsuda Takahisa, Ikematsu Hiroaki, Kaneko Kazuhiro, Ochiai Atsushi, Fujimori Takahiro, Sano Yasushi   +9 more
doaj   +1 more source

A Highly Predictive Model for Diagnosis of Colorectal Neoplasms Using Plasma MicroRNA: Improving Specificity and Sensitivity

Annals of Surgery, 2016
Objective: To develop a plasma-based microRNA (miRNA) diagnostic assay specific for colorectal neoplasms, building upon our prior work. Background: Colorectal neoplasms [colorectal cancer (CRC) and colorectal advanced adenoma (CAA)] frequently develop in
J. Carter, Henry Roberts, Jianmin Pan, J. Rice, James F. Burton, N. Galbraith, M. Eichenberger, J. Jorden, Peter Deveaux, Russell W. Farmer, Anna O Williford, Ziad Kanaan, S. Rai, S. Galandiuk   +13 more
semanticscholar   +1 more source