Results 81 to 90 of about 699,211 (296)

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

A screening model for advanced colorectal neoplasia based on tumor markers and inflammatory indices: a retrospective study with an online risk calculator

Frontiers in Oncology
ObjectivesThe goal is to design and validate a noninvasive screening model for advanced colorectal neoplasia(ACN) utilizing routine blood tumor markers and inflammatory indices, and to develop an online calculator for assessing individual risk.MethodsIn ...
Chang Zhang, Lei Jin, Shihao Wu, Liang Lu, Shui Jin   +4 more
doaj   +1 more source

Efficacy of capillary pattern type IIIA/IIIB by magnifying narrow band imaging for estimating depth of invasion of early colorectal neoplasms

BMC Gastroenterology, 2010
Background Capillary patterns (CP) observed by magnifying Narrow Band Imaging (NBI) are useful for differentiating non-adenomatous from adenomatous colorectal polyps.
Fu Kuang-I, Uraoka Toshio, Saito Yutaka, Emura Fabian, Matsuda Takahisa, Ikematsu Hiroaki, Kaneko Kazuhiro, Ochiai Atsushi, Fujimori Takahiro, Sano Yasushi   +9 more
doaj   +1 more source

The Genomics of colorectal cancer: State of the art [PDF]

, 2008
The concept of the adenoma-carcinoma sequence, as first espoused by Morson et al. whereby the development of colorectal cancer is dependent on a stepwise progression from adenomatous polyp to carcinoma is well documented.
Hodgson, SV, Hodgson, Shirley V, Beggs, AD, Beggs, Andrew D; id_orcid   +3 more
core   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Microsatellite Instability of Gastric and Colorectal Cancers as a Predictor of Synchronous Gastric or Colorectal Neoplasms

Gut and Liver, 2016
Background/Aims : Microsatellite instability (MSI) plays a crucial role in gastrointestinal carcinogenesis. The aim of this study was to clarify whether MSI is a useful marker for predicting synchronous gastric and colorectal neoplasms.
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Discrimination between Human Colorectal Neoplasms with a Dual-Recognitive Two-Photon Probe

, 2019
Colorectal cancer is a major cause of cancer-related deaths worldwide. Histologic diagnosis using biopsy samples of colorectal neoplasms is the most important step in determining the treatment methods, but these methods have limitations in accuracy and ...
Choi, H, Lee, K, Cho, MK, Lee, HW, Shin, SJ, Kim, HM, Noh, CK, Lim, CS   +7 more
core   +2 more sources

MALIGNANCY IN LARGE COLORECTAL LESIONS

Arquivos de Gastroenterologia, 2014
Context The size of colorectal lesions, besides a risk factor for malignancy, is a predictor for deeper invasion Objectives To evaluate the malignancy of colorectal lesions ≥20 mm.
Carlos Eduardo Oliveira dos SANTOS, Daniele MALAMAN, Tiago dos Santos CARVALHO, César Vivian LOPES, Júlio Carlos PEREIRA-LIMA   +4 more
doaj   +1 more source

Mean SF-12v2 scores of patients with colorectal neoplasms compared with age-sex matched controls from the Chinese general population.

, 2013
Mean SF-12v2 scores of patients with colorectal neoplasms compared with age-sex matched controls from the Chinese general population.
Dora L. W. Kwong (166235), Jensen T. C. Poon (389244), Carlos K. H. Wong (389242), Cindy L. K. Lam (389243)   +3 more
core   +1 more source