Results 151 to 160 of about 230,464 (218)

Structural Basis of Shiga Toxin Neutralization by Human Antibodies Targeting Canonical Receptor‐Binding and Non‐Canonical Assembly Sites

Advanced Science, EarlyView.
Cryo‐electron microscopy structures reveal two distinct neutralization mechanisms of fully human monoclonal antibodies targeting the Shiga toxin 1a B subunit. RDS059 occludes the Gb3 receptor‐binding site, whereas RDS045 engages a lateral quaternary epitope to disrupt holotoxin assembly.
Jianting Ke, Xin Li, Xiaoli Wang, Zhaoxia Huang, Shaojie Xue, Yuyang Liu, Jing Pan, Guowei Hu, Yayu Wang, Cheng Wang, Shoudeng Chen   +10 more
wiley   +1 more source

Regulating oxygen activation and catalytic kinetics in ZnCo₂O₄ nanozymes <i>via</i> Mn substitution: insights into the oxidase-like activity mechanism. [PDF]

RSC Adv
Hoang Thuc D, Huong Mai VT, Mai CQ, De PC, Tran VT, Ya V, Thi QH, Ngo XD, Hoang VT, Le AT.   +9 more
europepmc   +1 more source

Lattice Chloride Shielding and Reconstructed Phosphate Armor for Stable Seawater Electrolysis

Advanced Science, EarlyView.
A dual‐protection strategy integrating lattice Cl shielding with dynamically reconstructed phosphate armor enables selective OH adsorption and suppresses chloride‐induced corrosion during alkaline seawater electrolysis, delivering durable operation at industrial‐level current densities.
Yatao Yan, Yuxing Lin, Xing Chen, Shuo Yang, Ke Zhou, Jifang Chen, Lubin Ni, Ming Chen   +7 more
wiley   +1 more source

Radiation-Sensitive Thin Film Dosimeter Based on Polyvinyl Alcohol (PVA)/Hafnium Dioxide (HfO₂)/Silver Nitrate (AgNO₃) Composite: Colorimetric Characterization and Dose-Response Analysis for Low-Dose Gamma-Ray Applications. [PDF]

Polymers (Basel)
Alashrah S.
europepmc   +1 more source

DIXDC1 Promotes Lymphatic Metastasis and Resistance to Cuproptosis in Bladder Cancer Through Mediating DLAT

Advanced Science, EarlyView.
DIXDC1 drives bladder cancer progression by binding and stabilizing DLAT. This axis enhances NEK7 and CCNE2 mRNA stability to promote proliferation and lymphatic metastasis, while limiting copper‐induced DLAT oligomerization to reduce cuproptosis sensitivity, identifying DIXDC1 as a potential target linking metastasis with cuproptosis resistance ...
Hongqiong Li, Liang Cheng, Xiaole Lu, Haonan Dong, Shi Fu, Hongjin Shi, Mingsheng Liu, Chenwei Yang, Yuhang Huang, Zehua Chen, Yawei Zhang, Kaiwen Jie, Xiaoyue Zhang, Xiang Kui, Xinni Ye, Siting Chen, Xu Chen, Haifeng Wang   +17 more
wiley   +1 more source

Portable-Equipment-Assisted Colorimetric Hydrogel Kits Based on Quercetin-Reducing Silver Nanoparticles for Hg²⁺ Tests in Aquatic Products. [PDF]

ACS Omega
Ge Q, Zheng C, Hou C, Zhao X, Chen J, Han X, Ding J, Pu Y.   +7 more
europepmc   +1 more source

Chemotherapy‐Activated GSK3β‐DNMT1 Signaling Upregulates CD47 to Evade Macrophage Phagocytosis and Drive Temozolomide Resistance in Glioblastoma

Advanced Science, EarlyView.
Temozolomide treatment activates GSK3β, driving DNMT1 phosphorylation, destabilization, and CD47 promoter hypomethylation in glioblastoma. This epigenetic shift upregulates CD47, enabling TMZ‐treated GBM cells to evade macrophage phagocytosis, survive chemotherapy, and acquire resistance.
Jie Li, Shuai Ying, Yi Zhang, Jingjing Wang, Quan Wan, Lingli Gong, Daxing Xu, Zhenkun Yang, Hongnian Lu, Ying Yin, Xiangming Fang, Zhening Pu   +11 more
wiley   +1 more source

Polydopamine nanoparticle-based colorimetric-photothermal dual-mode lateral flow immunoassay for thromboembolism diagnosis. [PDF]

RSC Adv
Yin J, Qiu Y, Nie Y, Ju J, Ju Y, Wang F.
europepmc   +1 more source