Results 61 to 70 of about 282,094 (307)

Development of Optical Biosensor Technologies for Cardiac Troponin Recognition [PDF]

, 2015
Acute myocardial infarction (AMI) is the leading cause of death among cardiovascular diseases. Among the numerous attempts to develop coronary marker concepts into clinical strategies, cardiac troponin is known as a specific marker for coronary events ...
Abdolrahim, Mojgan, Alhosseini, Sanaz Naghavi, Rabiee, Mohammad, Tahriri, Mohammadreza, Tayebi, Lobat, Yazdanpanah, Sara   +5 more
core   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

A Foldable Thermoplastic Microdevice Integrating Isothermal Amplification and Schiff-Reaction-Based Colorimetric Assay for the Detection of Infectious Pathogens

Chemosensors
In this study, we introduce a plastic-based foldable microdevice that integrates loop-mediated isothermal amplification (LAMP) and a colorimetric assay based on the Schiff reaction to detect the genes of infectious bacteria.
Hee Mang Kim, Nae Yoon Lee
doaj   +1 more source

Rapid and semi-quantitative colorimetric loop-mediated isothermal amplification detection of ASFV via HSV color model transformation

Journal of Microbiology, Immunology and Infection, 2021
Background: African Swine Fever (ASF) is a highly contagious and lethal viral disease of swine, the presence of which in groups of pigs leads to enormous economic losses in the farming industry.
Ling-Shan Yu, Sheng-Yeh Chou, Hsing-Yu Wu, Yu-Cheng Chen, Yen-Hsu Chen   +4 more
doaj   +1 more source

Influence of hydroxyethyl starch (6% HES 130/0.4) administration on hematology and clinical chemistry parameters [PDF]

, 2008
Background: The chemical inertness of hydroxyethyl starch (HES) might cause interferences of the colloid with a variety of laboratory tests. We aimed to evaluate potential influences of HES 130/0.4, the newest HES type, on several common hematology and ...
Dieplinger, Benjamin, Haltmayer, Meinhard, Kreimeier, Uwe, Loeffler, Peter, Mueller, Thomas, Poelz, Werner, Rehm, Markus, Schimetta, Wolfgang   +7 more
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Highly Sensitive Colorimetric Detection of Ochratoxin A by a Label-Free Aptamer and Gold Nanoparticles

Toxins, 2015
A label-free aptamer-based assay for the highly sensitive and specific detection of Ochratoxin A (OTA) was developed using a cationic polymer and gold nanoparticles (AuNPs). The OTA aptamer was used as a recognition element for the colorimetric detection
Yunxia Luan, Jiayi Chen, Cheng Li, Gang Xie, Hailong Fu, Zhihong Ma, Anxiang Lu   +6 more
doaj   +1 more source

Pharmacological Rac1 inhibitors with selective apoptotic activity in human acute leukemic cell lines [PDF]

, 2017
Rac1 GTPase has long been recognized as a critical regulatory protein in different cellular and molecular processes involved in cancer progression, including acute myeloid leukemia.
Cabrera, Maia Diana Eliana, Cardama, Georgina Alexandra, Davio, Carlos Alberto, Echeverría, Emiliana Beatriz, Fernandez, Natalia Cristina, González, Nazareno, Lorenzano Menna, Pablo, Remes Lenicov, Federico   +7 more
core   +2 more sources

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

A Convenient and Label-Free Colorimetric Detection for L-Histidine Based on Inhibition of Oxidation of 3,3′,5,5′-Tetramethylbenzidine-H2O2 System Triggered by Copper Ions

Frontiers in Chemistry, 2021
L-Histidine (L-His) is an essential amino acid, which is used to synthesize proteins and enzymes. The concentration of L-His in the body is controlled to regulate tissue growth and repair of tissues.
Zhikun Zhang, Wenmeng Zhao, Cuixia Hu, Yapeng Cao, Yumin Liu, Qingju Liu   +5 more
doaj   +1 more source