Results 61 to 70 of about 18,208 (262)

Evaluation of the Antibacterial Activity of Annatto Dye on Some Pathogenic Bacteria

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2014
Background and Objectives:Today, disadvantages of antibiotics and synthetic preservatives have been identified, and researchers are seeking natural and safe alternatives.
Mahmoud Yolmeh, Mohammad Bagher Habibi Naja, Reza Farhoosh, Fereshteh Hosseini   +3 more
doaj  

The Substitution Effects of Tapioca Starch and Beetroot Powder as Filler On The Physical and Sensory Characteristics Of Chicken Sausage

Jurnal Ilmu dan Teknologi Hasil Ternak, 2020
Red beetroot is rich in phenolic acids and betalain as natural food-coloring agents. Freeze-dried red beetroot that ground into powder can be used as a source of natural coloring to substitute the use of synthetic food color additives as well as filler ...
Winny Swastike, Edi Suryanto, Rusman Rusman, Chusnul Hanim, Jamhari Jamhari, Yuny Erwanto, Jumari Jumari   +6 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Chemical-induced occupational asthma: A case series

Indian Journal of Allergy Asthma and Immunology
Exposure to a variety of chemicals is known to have adverse consequences, occupational asthma being one of them. Isocyanate exposure has been found to be associated with airways obstructive abnormalities, but Indian data in this context are scarce ...
Rakesh Kumar Singh, Parul Mrigpuri, Balakrishnan Menon, Mridul Sarma   +3 more
doaj   +1 more source

In search of the rainbow: Colored inks in surgical pathology

Indian Journal of Pathology and Microbiology, 2012
Introduction: Although surgical pathologists are aware of the multiple advantages that coloured inks contribute to surgical pathology practice, these coloured inks are not available in India and importing them is not a viable proposition.
Chandralekha Tampi
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Color Stability of Single-Shade Resin Composites: A Systematic Review of In Vitro Studies and Clinical Implications

Dentistry Journal
Background/Objectives: Modern restorative dentistry increasingly focuses on achieving optimal aesthetic integration while simplifying clinical procedures.
Mohamed Mohsen, Daniele Pergolini, Elena Bianca Nistor, Sara Habilaj, Guido Migliau, Flaminia Marini Grassetti, Antonella Polimeni, Gaspare Palaia   +7 more
doaj   +1 more source

A curious case of vanishing pigmented spots resembling lentigines

Indian Journal of Dermatopathology and Diagnostic Dermatology, 2019
Exogenous pigmentation due to arthropods or coloring agents/dyes may be mistaken for melanocytic lesions. Dermoscopy is a useful tool for the evaluation of pigmented lesions.
Meenakshi Batrani, Arshdeep, Asha Kubba, M Ramam   +3 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source