Results 1 to 10 of about 7,645 (216)

Risk Assessment of Food Coloring Agents on DNA Damage Using RAPD Markers [PDF]

open access: yesOpen Biotechnology Journal, 2009
In this study, faba bean (Vicia faba) seedlings were used as bioindicator to determine genotoxic effect of synthetic dyes currently used as food color additives in many countries. Novel short-term assays are required to substantiate the battery of assessment methods for evaluating the genotoxicity of candidate substances. Therefore, an attempt has been
exaly   +3 more sources

Safe Food Coloring Agent as an Alternative to Eosin Stain. [PDF]

open access: yesCureus
Introduction Eosin stain is a commonly used histological dye that selectively binds to acidic structures in cells, imparting a color between pink and red. Eosin stain can be harmful due to its chemical composition. Inhaling eosin stain in powder form or as aerosolized droplets can cause irritation in the respiratory tract. To overcome the toxic effects
Kar S   +5 more
europepmc   +3 more sources

Evaluation of photo-mutagenicity and photo-cytotoxicity of food coloring agents [PDF]

open access: yesMutagenesis, 2005
Pigments extracted from natural products are widely used for food coloration in Japan. An investigation concerning the photo-mutagenicity and photo-carcinogenicity of frequently used colorants in Japan was performed. Colorants examined were from Laccifer lacca (lac-color), Coccus cacti (cochineal-color), Carthamus tinctorius (carthamus yellow ...
Sakae, Arimoto-Kobayashi   +3 more
openaire   +2 more sources

Nutritional Study of Some Food Coloring Agents on Experimental Rats [PDF]

open access: yesInternational Journal of Nutrition and Food Sciences, 2014
This study was designed to recognize the biochemical and histological alterations in the liver and kidney of male rats due to daily oral intake (for 8 weeks) of beet and curcumin extracts as natural red and yellow color, edicol erythrosine and sunset yellow as recommended synthetic colors and two unknown commercial coloring agents (red and yellow). The
openaire   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Development of latent fingerprints using food coloring agents

open access: yesIP International Journal of Forensic Medicine and Toxicological Sciences
: The current study aims to explore the effectiveness of food dyes as potential agents for the formation of latent fingerprints on non-porous substrates.: The development of fingerprints is a long-established forensic technique crucial for identifying perpetrators. Traditional methods often use various powders to reveal latent fingerprints on different
Bhawna Sharma   +2 more
openaire   +1 more source

Effect of food preservative and food coloring agent on some physiological and hematological parameters in albino rats and the protective role of garlic [PDF]

open access: yesThe Egyptian Journal of Hospital Medicine, 2005
Most children, in the age of nursery consume food that contains both colorants and preservatives with great amount. This observation led us to study the interaction between sodium nitrite as a food preservative and sun set yellow as a coloring agent. The mixture of the two agents at the limited dose of each was found to be a lethal dose. So, 1/10 th of
Eman G.E. Helal, Mervat Abdel- Rahman
openaire   +1 more source

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