Results 61 to 70 of about 79,443 (280)

An exponential lower bound for Individualization-Refinement algorithms for Graph Isomorphism

, 2017
The individualization-refinement paradigm provides a strong toolbox for testing isomorphism of two graphs and indeed, the currently fastest implementations of isomorphism solvers all follow this approach.
Babai László, Benchmark, Engineering, McKay Brendan D., Miyazaki Takunari, Propagation Conflict, Zemlyachenko V. N.   +6 more
core   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Attentional Colorization Networks with Adaptive Group-Instance Normalization

Information, 2020
We propose a novel end-to-end image colorization framework which integrates attention mechanism and a learnable adaptive normalization function. In contrast to previous colorization methods that directly generate the whole image, we believe that the ...
Yuzhen Gao, Youdong Ding, Fei Wang, Huan Liang   +3 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Graph Coloring Algorithm Based on Minimal Cost Graph Neural Network

IEEE Access
The graph coloring problem functions as a fundamental and pivotal combinatorial optimization task and has played an essential role in various domains such as wireless spectrum management, register planning, and event scheduling.
Ming Gao, Jing Hu
doaj   +1 more source

Integrative Transcriptomic and Metabolomic Analysis Reveals the Molecular Mechanism of Red Maple (Acer rubrum L.) Leaf Coloring

Metabolites, 2023
This study employed a combination of ultraviolet spectrophotometry, LC-ESI-MS/MS system, and RNA-sequencing technology; the extracts and isolation of total RNA from the red and yellow leaf strains of red maple (Acer rubrum L.) at different developmental ...
Yuanyuan Luo, Min Deng, Xia Zhang, Damao Zhang, Wenqi Cai, Yuelin Long, Xingyao Xiong, Yanlin Li   +7 more
doaj   +1 more source

Super-polylogarithmic hypergraph coloring hardness via low-degree long codes

, 2013
We prove improved inapproximability results for hypergraph coloring using the low-degree polynomial code (aka, the 'short code' of Barak et. al. [FOCS 2012]) and the techniques proposed by Dinur and Guruswami [FOCS 2013] to incorporate this code for ...
Guruswami, Venkatesan, Harsha, Prahladh, Hastad, Johan, Srinivasan, Srikanth, Varma, Girish   +4 more
core   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Using Differential Evolution for the Graph Coloring

, 2012
Differential evolution was developed for reliable and versatile function optimization. It has also become interesting for other domains because of its ease to use. In this paper, we posed the question of whether differential evolution can also be used by
Brest, Janez, Fister, Iztok
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source