Results 101 to 110 of about 2,040,340 (300)
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
FEBS Open Bio, EarlyView.This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
Stability of slender columns on an elastic foundation with generalised end conditions
Ingeniería e Investigación, 2013 Slender columns’ lateral stability under compressive axial loads is presented, with uninhibited, partially inhibited and totally inhibited end side-sway, including the effects of semi-rigid connections and a uniformly distributed lateral elastic ...
J. Dario Aristizabal-Ochoa
doaj
FEBS Open Bio, EarlyView.We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli +3 more
wiley +1 more source
European Mathematical Society MagazineIn this issue, with a brief report from CERME13 and a presentation of the Thematic Working Group on Mathematics Teaching and Teacher Practice(s), TWG19, by the group leaders Reidar Mosvold, Mark Hoover, Helena Grundén, Siún Nic Mhuirí and Chrysoula ...
Mosvold, Reidar +4 more
openaire +2 more sources
FEBS Open Bio, EarlyView.Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Revista IBRACON de Estruturas e MateriaisThe effect of the semi-rigid connection between beams and columns on the global behavior of reinforced concrete (RC) structures was investigated. The relative rotations in the nodes of the spatial frames were determined using the analytical approach ...
Lucas Manoel +2 more
doaj +1 more source
Железобетонные конструкции, 2023 The impact of aggressive environments and, accordingly, the corrosion damage of concrete and reinforcing steel, the violation of adhesion between them in some areas lead to a change in the values of the limiting height of the compressed zone, which ...
S. Yu. Savin +2 more
doaj
FEBS Open Bio, EarlyView.We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.The brown marmorated stink bug, Halyomorpha halys, mainly secretes 4‐oxo‐(E)‐2‐hexenal, (E)‐2‐decenal, dodecane and tridecane, a mixture representative of that released by many heteropterans. We demonstrated that H. halys can synthesise these secretory components de novo using dietary glucose.
Haruna Fujimori, Koji Noge
wiley +1 more source
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source