Results 61 to 70 of about 4,745,065 (295)

Rapid quantitative procedure for removing cholesterol from butter fat

open access: yesJournal of Lipid Research, 1967
Cholesterol is rapidly and quantitatively removed from butter fat by passage of the fat in hexane or benzene solution over a column of Celite impregnated with an aqueous solution of digitonin.
D.P. Schwartz   +2 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Derivation of tropospheric methane from TCCON CH₄ and HF total column observations [PDF]

open access: yes, 2014
The Total Carbon Column Observing Network (TCCON) is a global ground-based network of Fourier transform spectrometers that produce precise measurements of column-averaged dry-air mole fractions of atmospheric methane (CH₄).
Bernath, P.   +13 more
core  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

The hybrid of floating stone column by numerical and physical evaluation [PDF]

open access: yes, 2018
Rapid population growth amplifying demand for accommodation and infrastructure has resulted in soft ground being increasingly used in construction. Problems related to soft ground can be remedied by adopting a ground improvement technique.
Meghzil, Sif Allah
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

The Effectiveness Of Using Column Formwork In A Multi-Story Building Construction Project

open access: yesRekayasa Sipil
Building the structural components is crucial for constructing a multi-story building. In the process of creating these components, which is commonly done through casting, a tool called formwork is required.
Muhammad Lawdy Dhiyaa Vansya   +2 more
doaj   +1 more source

Microminiature gas chromatographic column [PDF]

open access: yes, 1972
Techniques commonly used for fabrication of integrated circuits are utilized to produce long capillary tubes for microminiature chromatographs. Method involves bonding of flat silicon plate to top of spirally grooved silicon chip to close groove and form
Donaldson, R. W., Jr.
core   +1 more source

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