Results 91 to 100 of about 835,149 (319)

Noves dades sobre briòfits semifòssils de la Garrotxa [PDF]

open access: yes, 1989
Hom ha estudiat els briòfits semifòssils dels diferents nivells torbosos de quatre columnes sedimentàries extretes de dipòsits quaternaris de la zona volcànica de la Garrotxa.
Casas i Sicart, Creu   +1 more
core  

Oceanic methane biogeochemistry.

open access: yesChemical Reviews, 2007
This review shows that thermodynamic and kinetic constraints largely prevent large-scale methanogenesis in the open ocean water column. One example of open-ocean methanogenesis involves anoxic digestive tracts and fecal pellet microenvironments; methane ...
W. Reeburgh
semanticscholar   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

La libertad de enseñanza en la opinión pública durante la transición a la democracia en España

open access: yesEducació i Història: Revista d'Història de l'Educació, 2018
La nova realitat política d’Espanya després de la mort de Francisco Franco va obligar a emprendre canvis que afectarien les diferents esferes social, cultural, econòmica i, per descomptat i de forma directa, educativa.
Sara González Gómez   +1 more
doaj  

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

A review on Iberian and Italian occurrences of Quaternary lions

open access: yesEarth History and Biodiversity
The cave lion lineage records from Spain, Portugal, and Italy hold immense paleobiological significance, offering both recent insights and future potential for discoveries.
Joan Madurell-Malapeira   +7 more
doaj   +1 more source

Les coves de Cala Blanca (Ciutadella de Menorca) [PDF]

open access: yes, 2008
[cat] Les coves objecte d’aquest treball es troben ubicades en els terrenys situats al nord de cala Blanca, àrea urbanitzada que es localitza uns pocs quilòmetres al sud de Ciutadella.
Arnau, Pere   +3 more
core  

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

THE BISON SAMPLE FROM THE EARLY MIDDLE PLEISTOCENE SITE OF CONTRADA MONTICELLI (APULIA, SOUTHERN ITALY)

open access: yesRivista Italiana di Paleontologia e Stratigrafia
Several craniodental and postcranial Bovinae fossil remains coming from the early Middle Pleistocene Contrada Monticelli (CM) site (Castellana Grotte, BA) and preserved at the Museum of Earth Sciences at the University of Bari are here studied in detail
DARIO STEFANELLI   +5 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

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