Results 81 to 90 of about 15,848 (274)

A review on Iberian and Italian occurrences of Quaternary lions

Earth History and Biodiversity
The cave lion lineage records from Spain, Portugal, and Italy hold immense paleobiological significance, offering both recent insights and future potential for discoveries.
Joan Madurell-Malapeira, Ibon Barrasa-Morondo, Saverio Bartolini-Lucenti, Maria Prat-Vericat, Ainara Badiola, Antonio Rodríguez-Hidalgo, Asier Gómez-Olivencia, Lorenzo Rook   +7 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

THE BISON SAMPLE FROM THE EARLY MIDDLE PLEISTOCENE SITE OF CONTRADA MONTICELLI (APULIA, SOUTHERN ITALY)

Rivista Italiana di Paleontologia e Stratigrafia
Several craniodental and postcranial Bovinae fossil remains coming from the early Middle Pleistocene Contrada Monticelli (CM) site (Castellana Grotte, BA) and preserved at the Museum of Earth Sciences at the University of Bari are here studied in detail
DARIO STEFANELLI, LEONARDO SORBELLI, BENIAMINO MECOZZI, PATRIZIA MAIORANO, MARIA MARINO, RAFFAELE SARDELLA   +5 more
doaj   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Early Pleistocene freshwater fish from Dursunlu (Ilgın Basin, south-western Türkiye): Implications for early hominin dispersals out of Africa

Quaternary Environments and Humans
Dursunlu, located in the Ilgın Basin (south-western Türkiye), represents one of the most prolific sites to explore early human occupations in Anatolia. This paper describes the lacustrine fish assemblage from this site during the Early Pleistocene (Günz ...
Àngel Blanco-Lapaz, Àngel H. Luján, Elvan Demirci, Josep Sanjuan   +3 more
doaj   +1 more source

Publisher Correction: Assessment of the gene mosaicism burden in blood and its implications for immune disorders. [PDF]

Sci Rep, 2021
Solís-Moruno M, Mensa-Vilaró A, Batlle-Masó L, Lobón I, Bonet N, Marquès-Bonet T, Aróstegui JI, Casals F.   +7 more
europepmc   +1 more source

Elements bàsics de l'àlgebra lineal. Problemes per a la ciència de dades [PDF]

, 2019
Postprint (published ...
Pozo Montero, Francesc, Ripoll Missé, Jordi   +1 more
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

An Updated Review of Fossil Pollen Evidence for the Study of the Origin, Evolution and Diversification of Caribbean Mangroves. [PDF]

Plants (Basel), 2023
Rull V.
europepmc   +1 more source