Results 91 to 100 of about 1,934 (272)

Early Pleistocene freshwater fish from Dursunlu (Ilgın Basin, south-western Türkiye): Implications for early hominin dispersals out of Africa

open access: yesQuaternary Environments and Humans
Dursunlu, located in the Ilgın Basin (south-western Türkiye), represents one of the most prolific sites to explore early human occupations in Anatolia. This paper describes the lacustrine fish assemblage from this site during the Early Pleistocene (Günz ...
Àngel Blanco-Lapaz   +3 more
doaj   +1 more source

Publisher Correction: Assessment of the gene mosaicism burden in blood and its implications for immune disorders. [PDF]

open access: yesSci Rep, 2021
Solís-Moruno M   +7 more
europepmc   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

Columnes dòriques de la Sala Hispòstila del Park Guell

open access: yes, 1927
Amb el suport del Departament de Cultura de la Generalitat de Catalunya. Any 2022 ; Imatge positiva del negatiu original ; Títol proporcionat pel centre catalogador ; Publicada a: Josep F. Ràfols, F. Folguera i Grassi. Gaudí 1928 : J.F.
Editorial Canosa
core   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Maqueta de les Quatre Columnes Catalanes

open access: yes, 2009
Maqueta de: M. Luisa AguadoPuig Cadafalch, JosepPla de detall d'una de les quatre columnes catalanes, creades per l'arquitecte Josep Puig i Cadafalch. De dos metres de diàmetre i vint metres d'alçada son coronades amb capitells d'estil jònic.
Cunill, Julio   +1 more
core  

Interior del vestíbul en construcció de la Escuela Oficial de Nàutica de Barcelona. Amb columnes i alguns acabats. 1932

open access: yes, 1932
Vista del vestíbul en construcció de la Escuela Oficial de Náutica de Barcelona, Actual Facultat de Nàutica de Barcelona, des de l'escala principal.

core   +1 more source

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