Results 71 to 80 of about 15,848 (274)

Biomarkers and metal content in white seabream (Diplodus sargus) and its relationship with the occurrence of the Abnormal Tough Syndrome

Environmental Pollution and Management
There is still controversy on the cause of the incidence of abnormal tough syndrome (ATS) in some fish species, mainly the white seabream (Diplodus sargus). This work analyses the incidence of the ATS in white seabream in areas with a different extent of
Montserrat Solé, Sergi Omedes, Conxi Rodríguez-Prieto, María Lorenzo, Margarida Casadevall   +4 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Time in and for nature-based solutions. No quick fix solutions for complex ecological and social processes

Nature-Based Solutions
Nature-based solutions (NbS) are an increasingly widespread tool in environment and development policies. They embody the idea that nature and natural processes can be purposefully used by humans to provide solutions to pressing environmental and social ...
Ina Lehmann, Julia Grosinger, Steffen Bauer, Jean Carlo Rodríguez de Francisco, Katarzyna Negacz, Jonas Hein   +5 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Resultats dels treballs d'excavació de l'àrea central de la ciutat romana de Pollentia (Alcúdia, Mallorca): avanç preliminar [PDF]

, 1994
Les excavacions realitzades als darrers anys a l'àrea central de la ciutat romana de Pollentia han permès d'identificar una part del forum. Entre les restes descobertes destaca l'existencia del conjunt format pel Capitoli i el portie periferic que ...
Pollentia, Equip
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

La libertad de enseñanza en la opinión pública durante la transición a la democracia en España

Educació i Història: Revista d'Història de l'Educació, 2018
La nova realitat política d’Espanya després de la mort de Francisco Franco va obligar a emprendre canvis que afectarien les diferents esferes social, cultural, econòmica i, per descomptat i de forma directa, educativa.
Sara González Gómez, José Luis Hernández Huerta   +1 more
doaj  

Desenvolupament d'un servidor per la gestió de dades d'un videojoc [PDF]

, 2016
Aquest projecte de fi de grau consisteix en el disseny i creació d'un prototip de servidor que gestioni diverses dades provinents de clients d'un videojoc qualsevol.
Casanovas Ferrer, Victor
core  

El monestir de Sant Miquel de Fluvià i l’estructura del complex abacial [PDF]

, 2012
Fins fa ben poc, del monestir de Sant Miquel de Fluvià en coneixíem només l’església, que fa funcions de parròquia, i la torre campanar. Essent comés un dels monuments més significatius per conèixer l’arquitectura altmedieval dels comtats del nord-est de
Ferrer Welsh, Andrea, Tremoleda Trilla, Joaquim   +1 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source