Results 61 to 70 of about 15,848 (274)

La construcció dels espais de la bibliofília en l’articulisme de Joan Francesc Mira

open access: yesCultura, Lenguaje y Representación, 2017
Resum: La biblioteca ha estat un àmbit que ha fascinat l’ésser humà a causa dels diferents nivells interpretatius que aquest espai genera. Aquest treball revisa els assajos periodístics en què l’escriptor Joan Francesc Mira s’hi refereix a fi d’il ...
Sergi Serra Adsuara
doaj  

Column Chromatography [PDF]

open access: yesCurrent Protocols in Nucleic Acid Chemistry, 2000
AbstractColumn chromatography is used extensively in nucleic acid chemistry to purify or characterize products from chemical reactions. This appendix focuses on separations using silica gel or alumina. The procedures described include loading the column, assembling the apparatus, separating compounds and collecting fractions, and optimizing ...
openaire   +3 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Agronomic and organizational aspects of Barcelona’s community gardens

open access: yesFrontiers in Sustainable Food Systems
As food security becomes a growing concern in urban areas worldwide, municipal authorities are actively seeking ways to enhance and complement the food systems of their respective cities.
Diego Maximiliano Macall   +3 more
doaj   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

Noves descobertes a la catedral d'Egara : la catedral primitiva : la catedral visigòtica : les pintures de la segona catedral / [PDF]

open access: yes, 1948
Forma part del projecte: Biblioteca Digital d'Història de l'Art Hispànic (UAB)Localització de l'original: Universitat Autònoma de BarcelonaEstudi de l'arquitecte Josep Puig i Cadafalch entorn les noves descobertes a la catedral d'Egara.
Institut d'Estudis Catalans   +2 more
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

A Review on the Latest Early Pleistocene Carnivoran Guild from the Vallparadís Section (NE Iberia)

open access: yesQuaternary
The Vallparadís Section encompasses various geological layers that span a significant chronological range, extending from the latest Early Pleistocene to the early Middle Pleistocene, covering a timeframe from approximately 1.2 to 0.6 Ma.
Joan Madurell-Malapeira   +6 more
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

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