Results 91 to 100 of about 3,195,529 (338)

Strain and correlation of self-organized Ge_(1-x)Mn_x nanocolumns embedded in Ge (001)

open access: yes, 2010
We report on the structural properties of Ge_(1-x)Mn_x layers grown by molecular beam epitaxy. In these layers, nanocolumns with a high Mn content are embedded in an almost-pure Ge matrix. We have used grazing-incidence X-ray scattering, atomic force and
Arras, E.   +10 more
core   +3 more sources

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

The Lapidary Collection of the Taman Ancient Settlement: Identification Options of the Byzantine Reliefs

open access: yesВестник Волгоградского государственного университета. Серия 4. История, регионоведение, международные отношения, 2016
The paper presents heterogeneous carved stone blocks of the Middle Ages, originating from different parts of the Taman settlement. Some of them are preserved only in photos, the rest are kept in the collection of the Taman archaeological Museum, as well ...
Ekaterina Yu. Endoltseva   +1 more
doaj   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Emergence of physiological oscillation frequencies in a computer model of neocortex

open access: yesFrontiers in Computational Neuroscience, 2011
Coordination of neocortical oscillations has been hypothesized to underlie the binding essential to cognitive function. However, the mechanisms that generate neocortical oscillations in physiological frequency bands remain unknown.
Samuel A Neymotin   +11 more
doaj   +1 more source

Elongation of discotic liquid crystal strands and lubricant effects

open access: yes, 2013
After a short review on the physics of pulled threads and their mechanical properties, the paper reports and discusses on the strand elongation of disordered columnar phases, hexagonal or lamello-columnar, of small molecules or polymers.
Bhattacharyya, Surjya Sarathi   +1 more
core   +3 more sources

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Performance Evaluation of Reinforced Recycled Aggregate Concrete Columns under Cyclic Loadings

open access: yesApplied Sciences, 2019
Recycled concrete aggregates (RCAs) generated from construction and demolition activities have been recognized as a feasible alternative to natural aggregates (NAs).
Fan Wang   +5 more
doaj   +1 more source

Correlated and Decorrelated Positional and Orientational Order in the Nucleosomal Core Particle Mesophases

open access: yes, 2004
We investigate the orientational order of transverse polarization vectors of long columns of nucleosomal core particles and their coupling to positional order in high density mesophases discovered recently.
Lorman, V., Podgornik, R., Žekš, B.
core   +3 more sources

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

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