Results 81 to 90 of about 2,385,032 (294)

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Optimal Column-Based Low-Rank Matrix Reconstruction [PDF]

open access: yes, 2011
We prove that for any real-valued matrix $X \in \R^{m \times n}$, and positive integers $r \ge k$, there is a subset of $r$ columns of $X$ such that projecting $X$ onto their span gives a $\sqrt{\frac{r+1}{r-k+1}}$-approximation to best rank-$k ...
Ali Kemal Sinop   +3 more
core   +2 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

The Lapidary Collection of the Taman Ancient Settlement: Identification Options of the Byzantine Reliefs

open access: yesВестник Волгоградского государственного университета. Серия 4. История, регионоведение, международные отношения, 2016
The paper presents heterogeneous carved stone blocks of the Middle Ages, originating from different parts of the Taman settlement. Some of them are preserved only in photos, the rest are kept in the collection of the Taman archaeological Museum, as well ...
Ekaterina Yu. Endoltseva   +1 more
doaj   +1 more source

Asymptotics for incidence matrix classes

open access: yes, 2006
We define {\em incidence matrices} to be zero-one matrices with no zero rows or columns. A classification of incidence matrices is considered for which conditions of symmetry by transposition, having no repeated rows/columns, or identification by ...
Cameron, Peter   +2 more
core   +1 more source

Strain and correlation of self-organized Ge_(1-x)Mn_x nanocolumns embedded in Ge (001)

open access: yes, 2010
We report on the structural properties of Ge_(1-x)Mn_x layers grown by molecular beam epitaxy. In these layers, nanocolumns with a high Mn content are embedded in an almost-pure Ge matrix. We have used grazing-incidence X-ray scattering, atomic force and
Arras, E.   +10 more
core   +3 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Emergence of physiological oscillation frequencies in a computer model of neocortex

open access: yesFrontiers in Computational Neuroscience, 2011
Coordination of neocortical oscillations has been hypothesized to underlie the binding essential to cognitive function. However, the mechanisms that generate neocortical oscillations in physiological frequency bands remain unknown.
Samuel A Neymotin   +11 more
doaj   +1 more source

A Distinguisher-Based Attack of a Homomorphic Encryption Scheme Relying on Reed-Solomon Codes [PDF]

open access: yes, 2012
Bogdanov and Lee suggested a homomorphic public-key encryption scheme based on error correcting codes. The underlying public code is a modified Reed-Solomon code obtained from inserting a zero submatrix in the Vandermonde generating matrix defining it ...
Gauthier, Valérie   +2 more
core   +2 more sources

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