Results 91 to 100 of about 2,385,032 (294)

Conditioning of Random Block Subdictionaries with Applications to Block-Sparse Recovery and Regression

open access: yes, 2015
The linear model, in which a set of observations is assumed to be given by a linear combination of columns of a matrix, has long been the mainstay of the statistics and signal processing literature.
Bajwa, Waheed U.   +2 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Performance Evaluation of Reinforced Recycled Aggregate Concrete Columns under Cyclic Loadings

open access: yesApplied Sciences, 2019
Recycled concrete aggregates (RCAs) generated from construction and demolition activities have been recognized as a feasible alternative to natural aggregates (NAs).
Fan Wang   +5 more
doaj   +1 more source

Elongation of discotic liquid crystal strands and lubricant effects

open access: yes, 2013
After a short review on the physics of pulled threads and their mechanical properties, the paper reports and discusses on the strand elongation of disordered columnar phases, hexagonal or lamello-columnar, of small molecules or polymers.
Bhattacharyya, Surjya Sarathi   +1 more
core   +3 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

The Problem with the Linpack Benchmark Matrix Generator

open access: yes, 2008
We characterize the matrix sizes for which the Linpack Benchmark matrix generator constructs a matrix with identical ...
Jack J. Dongarra   +3 more
core   +7 more sources

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Mesoscale functional organization and connectivity of color, disparity, and naturalistic texture in human second visual area

open access: yeseLife
Although parallel processing has been extensively studied in the low-level geniculostriate pathway and the high-level dorsal and ventral visual streams, less is known at the intermediate-level visual areas. In this study, we employed high-resolution fMRI
Hailin Ai   +4 more
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Parametric Study on the Buckling of Unbraced Steel Frames under Fire Situation

open access: yesApplied Sciences
A parametric investigation of several unbraced steel frames with regular and irregular geometry subjected to elevated temperatures is carried out in this study to determine the most accurate procedure and buckling lengths to be considered during the ...
Thiago Silva   +3 more
doaj   +1 more source

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