Results 101 to 110 of about 2,566,141 (344)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Vowel Symmetry [PDF]

, 1976
Arrange the letters of the alphabet in columns of ...
Brooke, Maxey
core   +1 more source

Experimental Investigation of the Confinement of Concrete Columns with Welded Wire Reinforcement

Buildings
Traditional methods of construction for reinforced concrete columns utilize longitudinal steel bars and transverse ties. Field experience has shown that such a transverse reinforcement method is labor-intensive, time-consuming, and prone to ...
Abdelaziz Younes, Sami W. Tabsh
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Equal column sum and equal row sum dimension group realizations [PDF]

, 2013
David Handelman
openalex   +1 more source

ERME column

European Mathematical Society Magazine
In this issue, with a brief report from CERME13 and a presentation of the Thematic Working Group on Mathematics Teaching and Teacher Practice(s), TWG19, by the group leaders Reidar Mosvold, Mark Hoover, Helena Grundén, Siún Nic Mhuirí and Chrysoula ...
Mosvold, Reidar, Hoover, Mark, Grundén, Helen, Nic Mhuirí, Siún, Choutou, Chrysoula   +4 more
openaire   +1 more source

Concreto oncreto de alto desempenho aplicado em pilares sob carga excêntrica = High performance concrete applied in columns under eccentric loading

Acta Scientiarum: Technology, 2007
Este trabalho analisa o comportamento de pilares feitos com concreto de alto desempenho, com resistência média à compressão de 80 MPa, submetidos à compressão excêntrica.
Romel Dias Vanderlei, José Samuel Giongo   +1 more
doaj  

Conceptual and Applied Aspects of Water Retention Tests on Tailings Using Columns

Geosciences
The water retention capacity of porous materials is crucial in various geotechnical and environmental engineering applications such as slope stability analysis, landfill management, and mining operations.
Fernando A. M. Marinho, Yuri Corrêa, Rosiane Soares, Inácio Diniz Carvalho, João Paulo de Sousa Silva   +4 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source