Results 51 to 60 of about 2,566,141 (344)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Wolodymyr Sviatoslavovych’s Corsun «temples»

open access: yesВолинський благовісник, 2016
In this article one may consider the written testament dated 988, which tells about brought by kniaz Volodymyr from Corsun to Kyiv two copper temples and four copper horses.
Yurij Dyba
doaj  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Behaviour of Steel Grade S275JR Columns under the Influence of High-Temperature Creep

open access: yesMetals, 2018
This paper presents a test study focused on determining the influence of high-temperature creep on the buckling of grade S275JR columns. Both capacity and stationary-creep column tests were performed within the study.
Neno Torić   +3 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Column Introduction

open access: yesJournal of New Librarianship, 2017
column introduction on new generation of ...
Sarah Kennedy, Rick Mikulski
doaj  

Structural stability concepts in medieval and renaissance mechanics

open access: yesLatin American Journal of Solids and Structures
The identification of the origins of what we now call the theory of elastic stability is not an easy task. Most authors trace the origins to the pioneering work of Leonhard Euler in 1744, and some shift this origin to the experimental works of Petrus van
Luis A. Godoy
doaj   +1 more source

Study of the influence of compressive strength concrete on columns during the design of a multi-floor building

open access: yesRevista IBRACON de Estruturas e Materiais, 2019
This work aims to analyze the influence of the compressive strength of concrete columns in the design of a multi-floor building using the CAD/TQS computational tool.
G. M. FREGONEZI   +2 more
doaj   +2 more sources

Stability of the RC Column under Horizontal Impacts

open access: yesЖелезобетонные конструкции, 2023
Approaches to assessment of stability of reinforced concrete columns in case of horizontal emergency impact have been investigated. For this purpose, finite-element modeling of the system in spatial formulation, calculation according to the deformed ...
A. V. Alekseytsev
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

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