Results 51 to 60 of about 2,385,032 (294)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Column Introduction

open access: yesJournal of New Librarianship, 2017
column introduction on new generation of ...
Sarah Kennedy, Rick Mikulski
doaj  

Structural stability concepts in medieval and renaissance mechanics

open access: yesLatin American Journal of Solids and Structures
The identification of the origins of what we now call the theory of elastic stability is not an easy task. Most authors trace the origins to the pioneering work of Leonhard Euler in 1744, and some shift this origin to the experimental works of Petrus van
Luis A. Godoy
doaj   +1 more source

Study of the influence of compressive strength concrete on columns during the design of a multi-floor building

open access: yesRevista IBRACON de Estruturas e Materiais, 2019
This work aims to analyze the influence of the compressive strength of concrete columns in the design of a multi-floor building using the CAD/TQS computational tool.
G. M. FREGONEZI   +2 more
doaj   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Time-Dependent Deformations of Eccentrically Loaded Reinforced Concrete Columns

open access: yesInternational Journal of Concrete Structures and Materials, 2018
If reinforced concrete columns and walls in high-rise buildings are subjected to axial load for a sustained duration, long-term lateral deformation (or curvature) as well as axial shortening increase over time due to the creep and shrinkage of concrete ...
Tae-Sung Eom   +3 more
doaj   +1 more source

Stability of the RC Column under Horizontal Impacts

open access: yesЖелезобетонные конструкции, 2023
Approaches to assessment of stability of reinforced concrete columns in case of horizontal emergency impact have been investigated. For this purpose, finite-element modeling of the system in spatial formulation, calculation according to the deformed ...
A. V. Alekseytsev
doaj   +1 more source

LICOR-Liquid Columns' Resonances [PDF]

open access: yes, 1995
The aim of the experiment LICOR was the investigation of the axial resonances oi cylindrical liquid columns supported by equal circular coaxiaJ disks. In preparation ot the D-2 experiment a •heoreiical model has been developed, which exactly describes ...
Bauer, H.   +7 more
core   +1 more source

Mathematical modeling of thermal stabilization of vertical wells on high performance computing systems

open access: yes, 2013
Temperature stabilization of oil and gas wells is used to ensure stability and prevent deformation of a subgrade estuary zone. In this work, we consider the numerical simulation of thermal stabilization using vertical seasonal freezing columns.
Pavlova, Natalia V.   +2 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

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