Results 81 to 90 of about 3,195,529 (338)

Monotonic and Cyclic Seismic Analyses of Old-Type RC Columns with Short Lap Splices

Construction Materials
Reinforced concrete (RC) columns with short lap splices built in the early 1970s or before are known to have deficient seismic strength and ductility. These short lap splices are poorly confined and located right above the foundation level, where it is ...
Konstantinos G. Megalooikonomou
doaj   +1 more source

Column Chromatography [PDF]

Current Protocols in Nucleic Acid Chemistry, 2000
AbstractColumn chromatography is used extensively in nucleic acid chemistry to purify or characterize products from chemical reactions. This appendix focuses on separations using silica gel or alumina. The procedures described include loading the column, assembling the apparatus, separating compounds and collecting fractions, and optimizing ...
openaire   +3 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Nonlinear analysis of lightweight aggregate concrete columns

Budownictwo i Architektura, 2020
The paper presents a numerical analysis of deformability and load-bearing capacity of lightweight aggregate concrete (LWAC) elements subjected to bending with axial force.
Ewelina Kołodziejczyk, Tomasz Waśniewski   +1 more
doaj   +1 more source

Asymptotics for incidence matrix classes

, 2006
We define {\em incidence matrices} to be zero-one matrices with no zero rows or columns. A classification of incidence matrices is considered for which conditions of symmetry by transposition, having no repeated rows/columns, or identification by ...
Cameron, Peter, Prellberg, Thomas, Stark, Dudley   +2 more
core   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

The full-scale test of bearing structures of the shelter to assess the possibility of its further operation

Budownictwo i Architektura
Today, military operations continue in Ukraine, and the need for protective structures is increasing. The scientific work describes the structural scheme of the existing shelter, including the determination of cross-sectional dimensions, thicknesses ...
Andrii Kramarchuk, Borys Ilnytskyy , Oksana Lytvyniak   +2 more
doaj   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Stratigraphic columns and correlations for the Late Eocene - Oligocene Te Kuiti Group, central-western North Island, New Zealand [PDF]

, 2008
This report presents a compilation of stratigraphic columns for geological sections and outcrops of Late Eocene – Oligocene Te Kuiti Group units in central-western parts of North Island, New Zealand, between Port Waikato and Awakino.
Kamp, Peter J.J., Nelson, Campbell S., Tripathi, Anand Ratnakar Prasad   +2 more
core   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source