Results 61 to 70 of about 18,257,705 (233)

Grupo com irmãos de pessoas com necessidades especiais

open access: yesRevista Educação Especial, 2011
O relacionamento entre irmãos favorece o desenvolvimento de ambos porque a relação que se estabelece é de reciprocidade e ...
Karina Silva Molon, Luciane Najar Smeha
doaj   +3 more sources

Collagen‐Binding IL‐15 Immunocytokine Armed Oncolytic Adenovirus Establishes a Self‐Reinforcing Immunostimulatory Milieu to Potentiate Antitumor Immunity

open access: yesAdvanced Science, EarlyView.
Repurposing the dense tumor stroma from a physical barrier into an anchoring scaffold, an engineered oncolytic adenovirus encoding IL15C‐CBD overcomes the immunosuppressive microenvironment in triple‐negative breast cancer. Intratumoral viral replication secretes this collagen‐anchored immunocytokine, forming a localized cytokine depot.
Yaqi Yang   +14 more
wiley   +1 more source

Identification and abiotic stress response of a glutamine synthetase gene (AccGS) from the Asiatic honeybee, Apis cerana cerana (Hymenoptera: Apidae)

open access: yesEuropean Journal of Entomology, 2014
Glutamine synthetase (GS) is an essential detoxification enzyme that plays an important role in stress responses; however, little information regarding the function of this enzyme in hymenopteran insects is available.
Xiuling WANG   +4 more
doaj   +1 more source

UM ENCONTRO COM PAULO FREIRE: CAFÉ COM PAULO FREIRE SÃO LUIZ GONZAGA SABER DE EXPERIÊNCIA FEITO [PDF]

open access: yes, 2022
O texto tem como objetivo relatar como o educador Paulo Freire e o Café com Paulo Freire entrou na vida de uma professora de Educação Física que atua na formação inicial e permanente de professores ...
Maurente, Viviane Maciel Machado; Café com Paulo Freire São Luiz Gonzaga/RS
core  

A Metabolic‐Epigenetic Axis of AARS1/IGF2BP3‐K280 Lactylation Sustains Endometrial Cancer Stemness and Recurrence

open access: yesAdvanced Science, EarlyView.
Lactate‐driven endometrial cancer relapse is mediated by enzymatic protein modification. Elevated lactate levels activate AARS1, which catalyzes K280 lactylation of IGF2BP3, therefore stabilizing HMGA2 mRNA and promoting tumor stemness and recurrence.
Peng Jiang   +11 more
wiley   +1 more source

10-Year-Old Female with Acute Abdominal Pain with Pancreatic Mass

open access: yesCase Reports in Pediatrics, 2017
A previously healthy 10-year-old female presented to a local emergency department following three days of nausea and vomiting diagnosed with a solid pseudopapillary tumor. Solid pseudopapillary neoplasms are a rare form of pancreatic cystic neoplasm that
Charles K. Powers   +3 more
doaj   +1 more source

An Extracellular Pore‑Targeting Peptide Defines a Designable Allosteric Site in TRPV2

open access: yesAdvanced Science, EarlyView.
Structure‐guided peptide engineering yields Depiv2, a highly potent and subtype‐selective TRPV2 inhibitor that binds to the extracellular pore and remodels it into a closed, non‐conductive state. Depiv2 suppresses pathological cardiac hypertrophy, establishing the TRPV2 outer pore as a designable interface for selective peptide modulation.
Aiqin Zhu   +7 more
wiley   +1 more source

NINGUÉM SABE TUDO, NINGUÉM SABE NADA CURIOSANDO E ANDARILHANDO COM ANA MARIA ARAÚJO FREIRE - NITA FREIRE – [PDF]

open access: yes, 2022
Esta é uma entrevista-diálogo com Ana Maria Araújo Freire, Nita Freire, mas com um enfoque um pouco distinto das demais entrevistas que ela costuma conceder, pois vamos olhar/ad-mirar a Nita como intelectual e escritora, com intensa produção sobre o ...
de Avelar, Lucas Martins; Café com Paulo Freire Goiânia/GO   +2 more
core  

An Injectable and Self‐Reinforced Piezoelectric Hydrogel for Irregular Bone Defects Regeneration: Dynamic Epigenetic Regulation Approach

open access: yesAdvanced Science, EarlyView.
An injectable and self‐reinforcing RSF‐based piezoelectric hydrogel conforms to irregular bone defects and progressively strengthens in situ, overcoming the trade‐off between injectability and mechanical stability. Mechanical loading generates bioelectrical cues that promote P300‐mediated H3K9 acetylation and upregulate PTH1R expression, thereby ...
Yu‐Kai Huang   +15 more
wiley   +1 more source

PAULO FREIRE: SEU LEGADO E ENSINAMENTOS COM/POR FÁTIMA FREIRE - ENTREVISTA-DIÁLOGO COM FÁTIMA FREIRE [PDF]

open access: yes, 2021
Ser uma das filhas de Paulo Freire é uma boniteza só! Claro, é tão bonito quanto desafiador, pois, como disse Fátima, ter convivido com três pais – pai biológico, pai intelectual e pai mito – contribuiu para a construção de um ambiente de constante ...
BORGES, LIANA; Curadoria Nacional da Rede Nacional Café com Paulo Freire e Café do Centro Histórico POA/RS
core   +2 more sources

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