Results 81 to 90 of about 4,609,982 (234)

Shared decision making implementation: A case study analysis to increase uptake in New South Wales [PDF]

open access: yes, 2019
The aim of this study was to identify potential implementation interventions to increase the uptake of shared decision making (SDM) in clinical practice in New South Wales (NSW) Health. The Agency for Clinical Innovation hosted a full-day SDM masterclass
Dimopoulos-Bick, Tara   +4 more
core   +1 more source

A NeuroD1 AAV‐Based Gene Therapy for Functional Brain Repair in Alzheimer's Disease‐Like Non‐Human Primate Model

open access: yesAdvanced Science, EarlyView.
This study tests NeuroD1 AAV‐based gene therapy in a non‐human primate Alzheimer's disease model. The therapy prevents neuronal damage, inhibits hippocampal atrophy, and reduces neuroinflammation. It also repairs vascular and blood‐brain barrier damage, restores cerebrospinal fluid biomarkers, enhances hippocampal glucose metabolism, and improves ...
Zhouquan Jiang   +21 more
wiley   +1 more source

Circular Business Models and Sustainable Behavior: An Integrated Framework Based on the COM-B Model

open access: yesRevista de Gestão Social e Ambiental
Objective: This study aims to understand how circular business models can effectively influence consumer behavior towards sustainability, using the COM-B model (Capability, Opportunity, Motivation - Behavior) as an analytical framework. The central objective is to demonstrate that the integration of circular practices not only reduces environmental ...
Adayana Teberges Dantas Queiroga   +3 more
openaire   +1 more source

Efficient Electrocatalytic Conversion of CO2 to Pure Formic Acid Solutions via Strain‐Engineered Bismuth Nanosheets

open access: yesAdvanced Science, EarlyView.
Tensile‐strained bismuth nanosheets (TS‐BiNs) achieve a formate Faradaic efficiency of 92% at −1000 mA cm−2 and enable stable production of pure formic acid (HCOOH) in a solid‐state electrolyte reactor. Theoretical calculations reveal that the introduced strain lowers the energy barrier for *OCHO intermediate formation, fundamentally enhancing the ...
Shiqi Li   +16 more
wiley   +1 more source

Barriers and Facilitators to Antimicrobial Stewardship in Antibiotic Prescribing and Dispensing by General Practitioners and Pharmacists in Malta: A Systematic Review

open access: yesAntibiotics
Objective: Antimicrobial resistance (AMR) is a top ten threat to global public health, and Malta remains among the highest antibiotic-consuming countries in the European Union.
Brian Fenech, Daniel Gaffiero
doaj   +1 more source

Mortality due to ill-defined causes in Brazil (1979-2002) and a predictive model for age [PDF]

open access: yes, 2008
This study focused on the percentage of deaths due to ill-defined causes in Brazil, from 1979 to 2002. The objectives were to: (a) describe changes over the 24-year period; (b) identify the age group in which the percentage of ill-defined causes ...
Costa, Marli Ramos da   +1 more
core   +2 more sources

In Situ Stress‐Dispersing Hydrogel Millispheres via Load Redistribution to Restore Nucleus Pulposus Metabolic Homeostasis

open access: yesAdvanced Science, EarlyView.
Local stress concentration disrupts metabolic homeostasis and induces inflammation in the nucleus pulposus (NP), thereby accelerating intervertebral disc degeneration (IDD). A biomimetic HA/ChS hydrogel millimeter sphere (ChS@HM) is developed to enable synergistic stress dispersion and sustained hydration lubrication.
Ang Li   +4 more
wiley   +1 more source

Pro-Environmental Transformation of the Equine Sector—Facilitators and Challenges

open access: yesAnimals
To improve horse welfare and ensure a sustainable equestrian future, we need to understand human behavior in relation to the challenges of the sector. The purpose of this paper is to map and analyze how individuals within the equine sector in Sweden and ...
Susanna Hedenborg   +5 more
doaj   +1 more source

Exploring Telemedicine Acceptance: Applying the COM-B Model to Understand Cancer Patients’ Perspectives

open access: yes
The integration of telemedicine services into healthcare practices presents both opportunities and challenges, particularly in cancer care. The European eCAN Joint Action aims to provide a framework of recommendations for integrating telemedicine and remote monitoring into healthcare systems.
Farmaki, Anastasia   +9 more
openaire   +2 more sources

ANXA2‐mediated Phagocytosis Generates AR+ Macrophages to Confer Enzalutamide Resistance in Prostate Cancer

open access: yesAdvanced Science, EarlyView.
A novel resistance mechanism is mediated through phagocytosis of cancer cells by AR+ TAMs. This process, dependent on ANXA2, enables macrophages to acquire AR protein from engulfed tumor cells. The internalized AR translocates into the macrophage nucleus, where it binds directly to the IL‐6 promoter, augmenting IL‐6 transcription and secretion ...
Yong Luo   +13 more
wiley   +1 more source

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