Results 81 to 90 of about 3,564,000 (279)

In Situ Stress‐Dispersing Hydrogel Millispheres via Load Redistribution to Restore Nucleus Pulposus Metabolic Homeostasis

Advanced Science, EarlyView.
Local stress concentration disrupts metabolic homeostasis and induces inflammation in the nucleus pulposus (NP), thereby accelerating intervertebral disc degeneration (IDD). A biomimetic HA/ChS hydrogel millimeter sphere (ChS@HM) is developed to enable synergistic stress dispersion and sustained hydration lubrication.
Ang Li, Hui Yuan, Honglei Xiao, Xiaodong Liu, Wenguo Cui   +4 more
wiley   +1 more source

Betel vine (Piper betle L.) farmers’ marketing behaviour: An analysis using the com-b model and multiple linear regression technique

Journal of Horticultural Sciences
Betel leaf, known as the ‘Green Gold of India’, has significant commercial potential, poised to boost foreign exchange reserves. The present study aims to understand marketing dynamics and improve farmers’ incomes.
Padma S R, Sree Madhumitha G, Anusha V
doaj   +1 more source

ANXA2‐mediated Phagocytosis Generates AR+ Macrophages to Confer Enzalutamide Resistance in Prostate Cancer

Advanced Science, EarlyView.
A novel resistance mechanism is mediated through phagocytosis of cancer cells by AR+ TAMs. This process, dependent on ANXA2, enables macrophages to acquire AR protein from engulfed tumor cells. The internalized AR translocates into the macrophage nucleus, where it binds directly to the IL‐6 promoter, augmenting IL‐6 transcription and secretion ...
Yong Luo, Tianlong Luo, Lingfeng Li, Qi Sun, Dongquan Li, Shanhe Huang, Zonglin Li, Weilong Lin, Yuan Ou, Tao Du, Shengmeng Peng, Kewei Xu, Bisheng Cheng, Hai Huang   +13 more
wiley   +1 more source

Facilitating self-management support using the behaviour change wheel (BCW) to address healthcare professionals’ behaviour

International Journal of Educational Research Open
Background: Supporting self-management in healthcare practice is essential to improve chronic patients’ daily life experiences. Primary care professionals play an indispensable role in this. Nevertheless, supporting self-management in practice comes with
Lotte Timmermans, Peter Decat, Veerle Foulon, Ann Van Hecke, Mieke Vermandere, Birgitte Schoenmakers   +5 more
doaj   +1 more source

Noninvasive Focal Gene Delivery into the Cerebellum of Non‐Human Primates using Focused Ultrasound

Advanced Science, EarlyView.
Focal and non‐invasive viral vector delivery in non‐human primates remains a major challenge in translational neuroscience. Low‐intensity focused ultrasound was used to transiently open the blood–brain barrier and enable targeted gene delivery to the cerebellum.
Noelia Esteban‐García, José A. Pineda‐Pardo, Inés Trigo‐Damas, Marta Gutiérrez, Marta Castillo‐Ortiz, Megan Carrillo, Alejandro Reinares‐Sebastian, Víctor Medina‐Chavarrías, Itay Rachmilevitch, Masahiko Takada, José A. Obeso, Javier Blesa   +11 more
wiley   +1 more source

One‐Dimensional RuIrTe Nanotubes with Amorphous Surface as a Highly Active and Stable Electrocatalyst Toward Oxygen Evolution Reaction in Acidic Media

Advanced Science, EarlyView.
A rational etching‐induced reconstruction strategy is demonstrated to fabricate one‐dimensional RuIrTe ternary nanotubes with a unique amorphous‐crystalline heterostructure. This hierarchical architecture synergistically optimizes mass transport and electronic configurations, delivering record‐breaking performance in proton exchange membrane water ...
Zhi Liang Zhao, Zhe Zhang, Shaoxuan Yang, Jie Zhang, Qi Wang   +4 more
wiley   +1 more source

Folder 2: Model engine data sheets and operating instructions, B, 1936, 1948, 1997

, 1936
Illustration of a gas tank top from Bunch Model Airplane CO.
Bunch Model Airplane Co.
core   +1 more source

Using the COM-B model of behaviour to understand sitting behaviour in UK office workers

Sport & Exercise Psychology Review, 2018
Prolonged sedentary behaviour has established health risks; however many individuals spend long periods of time sitting at work. Qualitative researchers suggest that inconsistent effectiveness of interventions may be linked to an incomplete understanding of the nature of and factors influencing sedentary behaviour in the workplace.
MacDonald, Brad, Fitzsimons, Claire, Niven, Ailsa   +2 more
openaire   +2 more sources

G6PC Downregulation Promotes Renal Calcium Oxalate Stone Formation via Lactate‐Induced SNAIL1 K206 Lactylation and Epithelial‐Mesenchymal Transition

Advanced Science, EarlyView.
In renal calcium oxalate stone formation, G6PC downregulation leads to lactate accumulation. This lactate mediates CBP/p300‐dependent lactylation of SNAIL1 at K206, promoting its nuclear translocation. Nuclear SNAIL1 activates the TGF‐β/SMAD3 pathway, driving epithelial‐mesenchymal transition and fibrosis, which ultimately facilitates crystal ...
Kai Liu, Boming Zhang, Ruixin Fan, Chen Duan, Yangjun Zhang, Huahui Wu, Xiangyang Yao, Xiongmin Mao, Bo Li, Youmiao Zeng, Zhenzhen Xu, Yang Wang, Mengcheng Luo, Xinyu Xu, Ninghan Feng, Heng Li, Hua Xu   +16 more
wiley   +1 more source

Barriers and facilitators to prehabilitation participation among older adults undergoing major elective surgery: a qualitative study using the capability, opportunity, motivation - behavior model

BMC Geriatrics
Background Prehabilitation may improve patients’ functional capacity before surgery and enhance postoperative recovery. This study aimed to identify facilitators and barriers to participation in a multi-component prehabilitation program among older ...
Kuan-Yuan Wang, Christine Y. Nguyen, Kailin Xu, Yuchen Liu, Natalie Newmeyer, Sussan Alshanniek, Jennifer A. Palmer, Dae Hyun Kim   +7 more
doaj   +1 more source