Results 221 to 230 of about 570,074 (301)

Clinically significant hypoglycaemia in hospitalised adults: A multicentre study of 1205 episodes in the United Kingdom

open access: yesDiabetic Medicine, EarlyView.
Abstract Introduction and Objectives Inpatient hypoglycaemia is a serious complication of diabetes therapy, yet real‐world data on clinically significant episodes remain limited. The objectives of this study are (1) to describe the clinical and biochemical characteristics of clinically significant inpatient hypoglycaemia across multiple NHS sites, (2 ...
Charles Page   +16 more
wiley   +1 more source

Photoperiod‐Regulated Thermal Tolerance of the Non‐Diapausing Insect Ceratitis capitata (Diptera: Tephritidae)

open access: yesEntomologia Experimentalis et Applicata, EarlyView.
Developmental photoperiodic exposure (photoacclimation) from egg to adult emergence alters thermal tolerance in Ceratitis capitata. Flies reared under contrasting photoperiods (0:24, 8:16, 14:10, and 24:0 L:D) showed significant shifts in both CTmin and CTmax, whereas adult‐only photoacclimation affected CTmax but not CTmin.
Antonis G. Papadopoulos   +1 more
wiley   +1 more source

Love and the Basis of Dignity

open access: yesEuropean Journal of Philosophy, EarlyView.
Abstract It is often said that dignity is the ground of human rights. But what grounds dignity? According to proponents of the metaphysical view, dignity is grounded in our rational capacities, our sense of justice, or a disjunctive list of valuable capacities.
Jordan David Thomas Walters
wiley   +1 more source

ACTH suppression and adverse effects of cabergoline in horses with pituitary pars intermedia dysfunction

open access: yesEquine Veterinary Education, EarlyView.
Summary Background The diagnosis and management of pituitary pars intermedia dysfunction (PPID) in horses includes evaluating abnormal plasma concentrations of adrenocorticotrophic hormone (ACTH). Treatment commonly includes the oral dopamine agonist pergolide mesylate, which suppresses the pathologic overproduction of ACTH.
A. Bracken   +5 more
wiley   +1 more source

The tryptophan prenyltransferase ComQ from Bacillus subtilis 168 can prenylate daptomycin at Trp1

open access: yesThe FEBS Journal, EarlyView.
ComQ168 from Bacillus subtilis 168 catalyzes C‐terminal tryptophan farnesylation of ComX to generate a competence‐inducing pheromone. Recombinant ComQ168 also modifies cyclic peptides, including Daptomycin, likely at the N‐terminal tryptophan. Structural modeling highlights a C‐terminal binding region, supporting substrate promiscuity and establishing ...
Yanli Xu   +2 more
wiley   +1 more source

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