Results 51 to 60 of about 508,607 (232)

Waxy‐ or Putty‐Like Materials as a Novel Drug Preparation for Synthetic Cannabinoid Receptor Agonists: Detection in Prisons and In Vitro Cannabinoid Receptor Activity

open access: yesDrug Testing and Analysis, EarlyView.
Waxy‐ or putty‐like materials has emerged as a novel drug preparation for synthetic cannabinoids and other drugs in UK prisons. An in vitro CB1 bioassay was used to evaluate the CB1 activating potential of MDMB‐INACA and extracts from eight seized samples. MDMB‐INACA had moderate efficacy but low potency at CB1.
Axelle Timmerman   +9 more
wiley   +1 more source

Identification and Investigation of the Intrinsic Receptor Activation Potential and Metabolization of the New Oxo‐Pyridyl Synthetic Cannabinoid Receptor Agonist CH‐FUBBMPDORA

open access: yesDrug Testing and Analysis, EarlyView.
Another Chinese generic ban‐evading SCRA, CH‐FUBBMPDORA, has emerged. This study reports its first identification in Europe, its analytical characterization (NMR, Raman, FTIR, GC–MS, and HRMS), its cannabinoid activation potential in a βarr2 recruitment assay, and its metabolization profile.
Marie H. Deventer   +13 more
wiley   +1 more source

Comet Machholz (C/2004 Q2): morphological structures in the inner coma and rotation parameters

open access: yes, 2011
Extensive observations of comet C/2004 Q2 (Machholz) were carried out between August 2004 and May 2005. The images obtained were used to investigate the comet's inner coma features at resolutions between 350 and 1500 km/pixel.
C.B. Cosmovici   +25 more
core   +1 more source

Identification of Three Novel Tetrahydrocannabinol Analogs in the European Market

open access: yesDrug Testing and Analysis, EarlyView.
The major isolated ingredient of “CB9” was identified as [2‐(E)‐propen‐1‐yl]‐Δ8‐tetrahydrocannabinol‐acetate of “tresconol” as [2‐propen‐2‐yl]‐Δ9‐tetrahydrocannabinol and of “CBx” as [2‐propen‐2‐yl]‐Δ8‐tetrahydrocannabinol. These compounds have no available spectroscopic or chromatographic data and have never been identified in Cannabis plants, and ...
Evangelos Dadiotis   +4 more
wiley   +1 more source

Infant Death due to Cannabis Ingestion

open access: yesDrug Testing and Analysis, EarlyView.
ABSTRACT A child died in the emergency room of a local hospital a few hours after ingesting a substance the color of cork and the consistency of earth. At home, a modest amount of resinous substance was found. At the hospital, the child exhibited alterations in walking, balance, and consciousness.
Donata Favretto   +9 more
wiley   +1 more source

Coma imaging of comet P/Brorsen-Metcalf at Calar Alto in late July to mid August 1989 [PDF]

open access: yes
Comet P/Brorsen-Metcalf was observed on 1989/07/28+30 and on 1989/08/04+12(+14) with the 3.5 m telescope and the 0.8 m Schmidt camera at Calar Alto/Spain. The images exhibit a narrow plasma tail pointing into anti-solar direction.
Birkle, K.   +3 more
core   +1 more source

SOFIA Infrared Spectrophotometry of Comet C/2012 K1 (Pan-STARRS)

open access: yes, 2015
We present pre-perihelion infrared 8 to 31 micron spectrophotometric and imaging observations of comet C/2012 K1 (Pan-STARRS), a dynamically new Oort Cloud comet, conducted with NASA's Stratospheric Observatory for Infrared Astronomy (SOFIA) facility ...
de Pater, Imke   +10 more
core   +1 more source

DanGer Shock‐like profile predicts the outcome in ST‐elevation myocardial infarction‐related cardiogenic shock

open access: yesESC Heart Failure, EarlyView.
Flow chart illustrates the analysed patients as well as main baseline characteristics and outcomes comparing DanGer Shock‐like versus DanGer Shock‐unlike patients. The composite safety endpoint comprises severe bleeding, limb ischaemia, haemolysis, device failure, and worsening of aortic regurgitation. CS indicates cardiogenic shock.
Norman Mangner   +10 more
wiley   +1 more source

Comet P/Tempel: Some highlights and conclusions from the 1988 apparition [PDF]

open access: yes
From the brightness development and a sequence of imaging observations of the coma activity onset of comet P/Tempel 2 in 1988, it is concluded that there might have happened eruptive events of strong dust and gas outbursts during May and June 1988.
Baer, A.   +2 more
core   +1 more source

Near-UV OH Prompt Emission in the Innermost Coma of 103P/Hartley 2

open access: yes, 2017
The Deep Impact spacecraft fly-by of comet 103P/Hartley 2 occurred on 2010 November 4, one week after perihelion with a closest approach (CA) distance of about 700 km.
A'Hearn, Michael F.   +7 more
core   +1 more source

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