Results 41 to 50 of about 1,376 (293)

Intracerebral Hemorrhage Induces Monocyte TNF Signaling in Patients That Is Suppressed by BAF312

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intracerebral hemorrhage (ICH) causes high morbidity and mortality, with neurotoxic inflammation driven by infiltrating monocytes. This study is an in‐depth longitudinal examination of the immune response during the first week of ICH in the presence and absence of the immunomodulatory drug BAF312 (Siponimod).
Jonathan Howard DeLong, Sebastian Díaz‐Pérez, Kevin Navin Sheth, Jang‐Ho Cha, C. J. Malanga, Patricia G. M. Wagner, Nicole Pezous, Aurelie Hanin, Kyle B. Walsh, H. E. Hinson, Lauren Hachmann Sansing   +10 more
wiley   +1 more source

Health disparities in chronic liver disease

Hepatology, EarlyView., 2022
Abstract The syndemic of hazardous alcohol consumption, opioid use, and obesity has led to important changes in liver disease epidemiology that have exacerbated health disparities. Health disparities occur when plausibly avoidable health differences are experienced by socially disadvantaged populations.
Ani Kardashian, Marina Serper, Norah Terrault, Lauren D. Nephew   +3 more
wiley   +1 more source

Reserves, Injury Severity, and Outcomes in Traumatic Brain Injury: A CENTER‐TBI Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Reserve refers to the brain's ability to maintain function after an injury and strongly relates to traumatic brain injury (TBI) outcomes. This study examined (1) whether associations between pre‐injury reserve proxies and outcomes differed across injury severity categories, and (2) whether the impact of injury severity varied across ...
Natascha Ekdahl, Marika C. Möller, Lindsay Wilson, Anne Vik, Toril Skandsen, Jonas Stenberg, CENTER‐TBI participants and investigators   +6 more
wiley   +1 more source

Strongly Depleted Methanol and Hypervolatiles in Comet C/2021 A1 (Leonard): Signatures of Interstellar Chemistry?

The Planetary Science Journal, 2023
We measured the chemical composition of comet C/2021 A1 (Leonard) using the long-slit echelle grating spectrograph iSHELL/IRTF on 2021 December 20 and on 2022 January 8 and 9.
Sara Faggi, Manuela Lippi, Michael J. Mumma, Geronimo L. Villanueva   +3 more
doaj   +1 more source

Chemistry In Cometary Comae

, 1998
The published version is located at http://pubs.rsc.org/en/Content/ArticleLanding/1998/FD/a709289jSignificant gas-phase chemistry occurs in the comae of bright comets, as is demonstrated here for the case of Comet Hale–Bopp.
Schloerb, FP, Lovell, AJ, Irvine, William M., Matthews, HE, Jewitt, D, Dickens, JE, Bergin, EA, Senay, M   +7 more
core   +1 more source

Modeling Progressive Brain Volume Losses in Chronic Moderate Severe Traumatic Brain Injury: Extensive, but Attenuating

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Progressive brain atrophy has now been widely observed in the chronic stages of moderate–severe traumatic brain injury (msTBI), but there is only coarse information regarding its prevalence and magnitude, and whether rate of atrophy accelerates or attenuates across time. We examined these questions in a Canadian inception cohort from
Robin E. A. Green, Brenda Colella, Alana Changoor, David J. Mikulis, Adrienne Li, Kadeen Johns, Georges A. Monette   +6 more
wiley   +1 more source

Optical Imaging Polarimetry of Comet 21P/Giacobini–Zinner during Its 2018 Apparition

The Planetary Science Journal, 2023
We conducted polarimetric observations of comet 21P/Giacobini–Zinner in the optical wavelength region using the polarimetric imager PICO equipped with the 50 cm telescope for Public Outreach at the Mitaka Campus of the National Astronomical Observatory ...
Yoshiharu Shinnaka, Hideyo Kawakita, Hitomi Kobayashi, Reiko Furusho, Jun-ichi Watanabe   +4 more
doaj   +1 more source

Diffuse MRI Edema Predicts Relapse in Cerebral Amyloid Angiopathy–Related Inflammation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To identify MRI predictors of relapse and quantify relapse and mortality risk in cerebral amyloid angiopathy–related inflammation (CAA‐RI). A secondary objective was to assess the association between mycophenolate mofetil use and relapse risk. Methods We performed a retrospective cohort study of 36 patients with CAA‐RI treated at the
G. Abbas Kharal, Gowtham Yerneni, Kim J. Griffin, Nicolas Thompson, Ken Uchino, Irene Katzan, Dolora Wisco, Abeer Farrag, Jayashree Sundarajan, Andrew Russman, M. Shazam Hussain   +10 more
wiley   +1 more source

Acute Endocrine Alterations After Traumatic Brain Injury and 6‐Month Functional Outcome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Acute multi‐axis endocrine alterations after traumatic brain injury (TBI) remain incompletely characterized. This study aimed to examine their temporal patterns and explore their associations with 6‐month functional outcome and early inflammatory markers.
Biao Xu, Peng Guo, Rui Pan, Zhenghao Wang, Jingchao Zhou, Pengcheng Zhang, Xingzhe Zhang, Qinghua Zhang, Haibin Ma, Zhanfeng Niu   +9 more
wiley   +1 more source

Observations of [O I] Emission in Comets C/2014 Q2 (Lovejoy) and C/2007 N3 (Lulin): Possible Influence of Solar Activity on Oxygen Line Ratios

The Planetary Science Journal
Observing [O i ] emission to calculate an oxygen line ratio has been proposed as a potential proxy for direct CO _2 measurement in comets. However, the photochemistry governing [O i ] release into the coma is not well understood, and using theoretical ...
Ella J. Mayfield, Adam J. McKay, Michael S. P. Kelley, Anita L. Cochran   +3 more
doaj   +1 more source