Enhanced anticancer activity of a combination of docetaxel and Aneustat (OMN54) in a patient-derived, advanced prostate cancer tissue xenograft model. [PDF]
, 2013 The current first-line treatment for advanced metastatic prostate cancer, i.e. docetaxel-based therapy, is only marginally effective. The aim of the present study was to determine whether such therapy can be improved by combining docetaxel with Aneustat (
Collins, Colin C +9 more
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Questions of optimal choice of NSAIDs in pediatric practice
Медицинский совет, 2014 The article tells about the basic mechanisms of inflammation, defines the scheme for rational care and symptomatic treatment of children with symptoms of pain and fever, antipyretic action of antipyretic analgesics.
E. M. Ovsyannikova, N. A. Korovina
doaj +1 more source
Symptomatic treatment of acute respiratory viral infections
Медицинский совет, 2015 The most common causes of respiratory diseases are acute respiratory viral infections (ARVI). According to the World Health Organization, every adult suffers from ARVI twice a year, while an average child gets sick 3 times more often. Each year in Russia,
O. V. Goncharova, G. V. Kuranov
doaj +1 more source
Multistrain models predict sequential multidrug treatment strategies to result in less antimicrobial resistance than combination treatment [PDF]
, 2016 Background Combination treatment is increasingly used to fight infections caused by bacteria resistant to two or more antimicrobials. While multiple studies have evaluated treatment strategies to minimize the emergence of resistant strains for single ...
Ahmad, Amais +7 more
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Pharmacological and non-pharmacological treatments for ARVI
Медицинский совет, 2015 ARVI is one of the most common diseases worldwide. Search for adequate treatment remains an urgent public healthcare problem globally. The main task is still an effective and safe relief of ARVI symptoms, for the purpose of which both pharmacological and
I. L. Lazarevich
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A survey of Top 200 Drugs—Inconsistent Practice of Drug Strength Expression for Drugs Containing Salt Forms [PDF]
, 2012 Many ionizable drugs are developed and marketed as salt forms. However, there are no clear US regulatory guidelines on drug strength labeling for salts. The strengths of some drugs are expressed as salts and some as free acids/bases.
Prohotsky, Daniel, Zhao, Fang
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Combination therapy for cough and bronchial obstruction in childhood
Медицинский совет, 2019 The inflammatory process in the bronchial mucosa of various origins (infectious, allergic, irritative, etc.) cause changes in the sputum production and its rheological properties, slowing of mucociliary clearance.
Yu. L. Mizernitskiy +2 more
doaj +1 more source
Activity of oxantel pamoate monotherapy and combination chemotherapy against Trichuris muris and hookworms : revival of an old drug [PDF]
, 2013 BACKGROUND: It is widely recognized that only a handful of drugs are available against soil-transmitted helminthiasis, all of which are characterized by a low efficacy against Trichuris trichiura, when administered as single doses.
Adelfio, R. +5 more
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Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2018 Introduction. An actual task of modern medicine is the development of treatment methods of the central nervous system diseases. The solution of this problem was the creation of new, more effective neuropsychotropic drug that shows pronounced ...
L. I. Kucherenko +4 more
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In silico and in vitro drug screening identifies new therapeutic approaches for Ewing sarcoma. [PDF]
, 2016 The long-term overall survival of Ewing sarcoma (EWS) patients remains poor; less than 30% of patients with metastatic or recurrent disease survive despite aggressive combinations of chemotherapy, radiation and surgery.
Alturkmani, Hani +11 more
core +3 more sources