Results 1 to 10 of about 9,546,669 (393)

Combination therapy in the treatment of hypertension

Drugs in Context, 2018
Hypertension is a major preventable risk factor for atherosclerosis and ischemic heart disease. Although modern and effective antihypertensive drugs are available, most patients remain with a suboptimal blood pressure control.
Alberto Francisco Rubio-Guerra
doaj   +2 more sources

Radionuclide-labelled nanoparticles for cancer combination therapy: a review [PDF]

Journal of Nanobiotechnology
Radionuclide therapy (RT) is widely used to advanced local cancers. However, its therapeutic efficacy is limited to the radiation resistance of cancer cells.
Na Sun, Tao Wang, Song Zhang
doaj   +2 more sources

Multifunctional metal-organic framework (MOF)-based nanoplatforms for cancer therapy: from single to combination therapy

Theranostics, 2023
Cancer remains a severe threat to human health. To date, although various therapeutic methods, including radiotherapy (RT), chemotherapy, chemodynamic therapy (CDT), phototherapy, starvation therapy, and immunotherapy, have entered a new stage of rapid ...
Jie Yang, Dihua Dai, Xi Zhang, Lesheng Teng, Lianjun Ma, Ying‐Wei Yang   +5 more
semanticscholar   +1 more source

Nivolumab Combination Therapy in Advanced Esophageal Squamous-Cell Carcinoma.

New England Journal of Medicine, 2022
BACKGROUND First-line chemotherapy for advanced esophageal squamous-cell carcinoma results in poor outcomes. The monoclonal antibody nivolumab has shown an overall survival benefit over chemotherapy in previously treated patients with advanced esophageal
Y. Doki, J. Ajani, Ken Kato, Jianming Xu, L. Wyrwicz, S. Motoyama, T. Ogata, H. Kawakami, Chih-Hung Hsu, A. Adenis, F. El hajbi, M. Di Bartolomeo, M. Braghiroli, E. Holtved, S. A. Ostoich, H. R. Kim, Masaki Ueno, W. Mansoor, Wen-Chi Yang, Tianshu Liu, J. Bridgewater, T. Makino, I. Xynos, Xuan Liu, M. Lei, K. Kondo, A. Patel, J. Gricar, I. Chau, Y. Kitagawa   +29 more
semanticscholar   +1 more source

Radiation-induced tumor immune microenvironments and potential targets for combination therapy

Signal Transduction and Targeted Therapy, 2023
As one of the four major means of cancer treatment including surgery, radiotherapy (RT), chemotherapy, immunotherapy, RT can be applied to various cancers as both a radical cancer treatment and an adjuvant treatment before or after surgery.
Siyu Guo, Yihan Yao, Yang Tang, Zengfeng Xin, Dang Wu, C. Ni, Jian Huang, Q. Wei, Ting Zhang   +8 more
semanticscholar   +1 more source

Combination therapy with immune checkpoint inhibitors (ICIs); a new frontier

Cancer Cell International, 2022
Recently, immune checkpoint inhibitors (ICIs) therapy has become a promising therapeutic strategy with encouraging therapeutic outcomes due to their durable anti-tumor effects.
S. Vafaei, A. Zekiy, R. Khanamir, B. Zaman, Arman Ghayourvahdat, Hannaneh Azimizonuzi, M. Zamani   +6 more
semanticscholar   +1 more source

Independent Drug Action in Combination Therapy: Implications for Precision Oncology

Cancer Discovery, 2022
Combination therapies are superior to monotherapy for many cancers. This advantage was historically ascribed to the ability of combinations to address tumor heterogeneity, but synergistic interaction is now a common explanation as well as a design ...
D. Plana, A. Palmer, P. Sorger
semanticscholar   +1 more source

CAR-T cell combination therapy: the next revolution in cancer treatment

Cancer Cell International, 2022
In recent decades, the advent of immune-based therapies, most notably Chimeric antigen receptor (CAR)-T cell therapy has revolutionized cancer treatment.
Maysoon Al-Haideri, Santalia Banne Tondok, Salar Hozhabri Safa, Ali Heidarnejad Maleki, S. Rostami, A. Jalil, M. Al-Gazally, Fahad Alsaikhan, J. Rizaev, T. M. Mohammad, S. Tahmasebi   +10 more
semanticscholar   +1 more source

Synergetic Thermal Therapy for Cancer: State-of-the-Art and the Future

Bioengineering, 2022
As a safe and minimal-invasive modality, thermal therapy has become an effective treatment in cancer treatment. Other than killing the tumor cells or destroying the tumor entirely, the thermal modality results in profound molecular, cellular and ...
Qizheng Dai, Bo Cao, Shiqing Zhao, Aili Zhang   +3 more
doaj   +1 more source

Treatment of Uterine Fibroid Symptoms with Relugolix Combination Therapy.

New England Journal of Medicine, 2021
BACKGROUND Uterine fibroids are a common cause of heavy menstrual bleeding and pain. Treatment with the combination of relugolix (an oral gonadotropin-releasing hormone-receptor antagonist), estradiol, and norethindrone acetate, administered once daily ...
A. Al-Hendy, A. Lukes, A. Poindexter, R. Venturella, C. Villarroel, H. Critchley, Yulan Li, L. McKain, J. A. Arjona Ferreira, Andria G. M. Langenberg, R. Wagman, E. Stewart   +11 more
semanticscholar   +1 more source