Results 41 to 50 of about 6,383,361 (296)

Social Functioning Within the First Years After Pediatric Brain Tumor Diagnosis and the Relationship With Family Psychosocial Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben, Marisa H. Huisman, Martha A. Grootenhuis, Femke K. Aarsen, Marita Partanen   +4 more
wiley   +1 more source

Roles of STAT3 in the pathogenesis and treatment of glioblastoma

Frontiers in Cell and Developmental Biology, 2023
Glioblastoma (GBM) is the most malignant of astrocytomas mainly involving the cerebral hemispheres and the cerebral cortex. It is one of the fatal and refractory solid tumors, with a 5-year survival rate of merely 5% among the adults. IL6/JAK/STAT3 is an
Weijia Fu, Weijia Fu, Weijia Fu, Xue Hou, Xue Hou, Xue Hou, Lihua Dong, Lihua Dong, Lihua Dong, Wei Hou, Wei Hou, Wei Hou   +11 more
doaj   +1 more source

The effect of oral clindamycin and rifampicin combination therapy in patients with hidradenitis suppurativa in Singapore [PDF]

, 2018
Harumi Ochi, Lixian Chris Tan, Hazel H Oon Department of Dermatology, National Skin Centre, Singapore Abstract: Hidradenitis suppurativa (HS) is a chronic inflammatory disease of follicular occlusion characterized by abscesses, draining sinuses,
Lixian Tan, Hazel Oon, Tan LC, Harumi Ochi, Ochi H, Oon HH   +5 more
core   +1 more source

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source

Life expectancy of persons receiving combination antiretroviral therapy in low-income countries: a cohort analysis from Uganda [PDF]

, 2011
Little is known about the effect of combination antiretroviral therapy (cART) on life expectancy in sub-Saharan ...
Chan, Keith, Bakanda, Celestin, Mills, Edward J, Cooper, Curtis L., Dybul, Mark, Hogg, Robert S., Nachega, Jean B, Ford, Nathan, Nachega, Jean B., Cooper, Curtis L, Birungi, Josephine, Mills, Edward J., Hogg, Robert S   +12 more
core   +1 more source

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

The Impact of the COVID‐19 Pandemic on Childhood Cancer Survival: A Population‐Based Assessment of Survival Patterns Between 2015 and 2023 in Germany

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Numerous international studies have reported declines in new cancer diagnoses, delayed diagnoses and disruptions in cancer treatment following the implementation of COVID‐19 pandemic public health measures, raising concerns that these effects may ultimately contribute to increased cancer mortality.
Friederike Erdmann, Maike Wellbrock, Javier Louro, Arndt Borkhardt, Martin Schrappe, Claudia Trübenbach, Desiree Grabow, Cécile M. Ronckers, Joachim Schüz   +8 more
wiley   +1 more source

Combination Drug Therapy for Benign Prostatic Hyperplasia (BPH)

The Annals of African Surgery, 2010
Background: The incidence of benign prostatic hyperplasia peaks 80% in old age. Bothersome symptoms and progression to acute urinary retention and need for surgery are important concerns.
Oliech J.S.
doaj  

Co-Delivery of Paclitaxel Prodrug, Gemcitabine and Porphine by Micelles for Pancreatic Cancer Treatment via Chemo-Photodynamic Combination Therapy

Pharmaceutics, 2022
Pancreatic carcinoma is an aggressive subtype of cancer with poor prognosis, known for its refractory nature. To address this challenge, we have established a stable nanoplatform that combines chemotherapy with photodynamic therapy (PDT) to achieve ...
Qiwei Wu, Xiaodong Ma, Wenhui Zhou, Rong Yu, Jessica M. Rosenholm, Weizhong Tian, Lirong Zhang, Dongqing Wang, Hongbo Zhang   +8 more
doaj   +1 more source

Are Tanzanian patients attending public facilities or private retailers more likely to adhere to artemisinin-based combination therapy? [PDF]

, 2015
BACKGROUND: Artemisinin combination therapy (ACT) is first-line treatment for malaria in most endemic countries and is increasingly available in the private sector. Most studies on ACT adherence have been conducted in the public sector, with minimal data
Catherine Goodman, Schellenberg, David, Kalolella, Admirabilis, Katia Bruxvoort, Bruxvoort, Katia, Matthew Cairns, Festo, Charles, Charles Festo, David Schellenberg, Peter Lyaruu, S Kachur, Goodman, Catherine, Kenani, Mitya, Kachur, S Patrick, Lyaruu, Peter, Admirabilis Kalolella, Mitya Kenani, Cairns, Matthew   +17 more
core   +1 more source