Results 31 to 40 of about 6,383,361 (296)

Combination Therapy Is Not Associated with Decreased Mortality in Infectious Endocarditis: A Systematic Review and Meta-Analysis

Microorganisms
Untreated infective endocarditis (IE) is uniformly fatal. The practice of combination antibiotic therapy for IE is recommended by treatment guidelines but largely unsupported by high-quality evidence.
Parisa Farahani, Felicia Ruffin, Mohammad Taherahmadi, Maren Webster, Rachel E. Korn, Sarah Cantrell, Lana Wahid, Vance G. Fowler, Joshua T. Thaden   +8 more
doaj   +1 more source

Omadacycline Potentiates Clarithromycin Activity Against Mycobacterium abscessus

Frontiers in Pharmacology, 2021
Mycobacterium abscessus is a difficult respiratory pathogen to treat, when compared to other nontuberculus mycobacteria (NTM), due to its drug resistance.
Bui Thi Bich Hanh, Nguyen Thanh Quang, Yujin Park, Bo Eun Heo, Seunghyeon Jeon, June-Woo Park, Jichan Jang, Jichan Jang   +7 more
doaj   +1 more source

Optimal lipid modification: the rationale for combination therapy [PDF]

, 2005
James M Backes1, Cheryl A Gibson2, Patricia A Howard31Department of Pharmacy Practice, Lipid, Atherosclerosis, Metabolic and LDL Apheresis Center, University of Kansas Medical Center, Kansas City, KS, USA; 2Department of Internal Medicine, University of ...
James M Backes, Backes, James M., Howard, Patricia A., Cheryl A Gibson, Gibson, Cheryl A., Patricia A Howard   +5 more
core   +1 more source

Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine, Hallie Coltin, Sylvia Cheng, Lucie Lafay‐Cousin, Vanan Issai Magimairajan, Craig Erker, Stéphanie Vairy, Lynette Bowes, Adam Fleming, Donna Johnston, Sarah McKillop, Roona Sinha, Julie Bennett, Christina Coleman, Laura Wheaton, Shayna Zelcer, Samuele Renzi, Thai Hoa Tran   +17 more
wiley   +1 more source

Progress in the Application of Nanomaterials in Tumor Treatment

Biomedicines
Cancer continues to pose a major global health burden, with conventional therapeutic modalities such as surgical resection, chemotherapy, radiotherapy, and immunotherapy often hindered by limited tumor specificity, substantial systemic toxicity, and the ...
Xingyu He, Lilin Wang, Tongtong Zhang, Tianqi Lu   +3 more
doaj   +1 more source

Modern Principles of Treatment of Uncontrolled Hypertension

Рациональная фармакотерапия в кардиологии, 2019
Despite the current possibilities of using different classes of antihypertensive drugs that effectively reduce blood pressure and significantly improve the long-term prognosis of patients, the problem of uncontrolled arterial hypertension has not lost ...
V. I. Podzolkov, A. I Tarzimanova, Z. O. Georgadze   +2 more
doaj   +1 more source

Nanoparticle-Based Combination Therapy for Melanoma

Frontiers in Oncology, 2022
Melanoma is a cutaneous carcinoma, and its incidence is rapidly increasing with every year. The treatment options for melanoma have been comprehensively studied.
Hongbo Chen, Kai Hou, Jing Yu, Le Wang, Xue Chen   +4 more
doaj   +1 more source

In-hospital safety in field conditions of Nifurtimox Eflornithine Combination Therapy (NECT) for T. B. Gambiense Sleeping Sickness [PDF]

, 2012
Trypanosoma brucei (T.b.) gambiense Human African trypanosomiasis (HAT; sleeping sickness) is a fatal disease. Until 2009, available treatments for 2(nd) stage HAT were complicated to use, expensive (eflornithine monotherapy), or toxic, and ...
Kisala, M, Schmid, C., Kisala, M., Mordt, O. V., Ismael Lumpungu, Mutanda, S, Mays Kisala, Kande, V, Nganzobo Pathou, Kuemmerle Andrea, Blum Johannes, Medard Ilunga, Nono Mubwa, Lumpungu Ismael, Mubwa Nono, Mordt Olaf Valverde, Schmid Caecilia, Mubwa, N, Blesson Severine, Wilfried Mutombo, Nganzobo, P., Mutombo Wilfried, Victor Kande, Mordt, O V, Tete Digas, Tete, D, Blesson, S, Kümmerle, A., Ilunga Medard, Schmid, C, Ilunga, M., Kuemmerle, A, Sylvain Mutanda, Ghabri, S, Ghabri, S., Andrea Kuemmerle, Lumpungu, I, Salah Ghabri, Kande, V., Johannes Blum, Lumpungu, I., Ghabri Salah, Blum, J, Digas Tete, Mubwa, N., Mutanda, S., Pathou Nganzobo, Ilunga, M, Caecilia Schmid, Tete, D., Nganzobo, P, Blum, J., Mutombo, W., Mutanda Sylvain, Kisala Mays, Blésson, S., Olaf Valverde Mordt, Severine Blesson, Kande Victor, Mutombo, W, Kisala M, Kuemmerle A, Mubwa N, Blesson S, Ghabri S, Kande V, Nganzobo P, Ilunga M, Mutombo W, Lumpungu I, Schmid C, Mordt OV, Mutanda S, Blum J, Tete D   +74 more
core   +1 more source

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani, Rachel K. Peterson, Avani D. Rao, Laurie J. McKenzie, Ahmed Magdy Elmotayam, Leslie Chang, Michael Roth, Susan L. McGovern   +7 more
wiley   +1 more source

Laboratory and clinical predictors of disease progression following initiation of combination therapy in HIV-infected adults in Thailand [PDF]

, 2012
Background Data on determinants of long-term disease progression in HIV-infected patients on antiretroviral therapy (ART) are limited in low and middle-income settings. Methods Effects of current CD4 count, viral load and haemoglobin and diagnosis
Jourdain, G, Lallemant, Marc, Sudanee Buranabanjasatean, Jourdain, Gonzague, Duong, Trinh, Tansuphasawasdikul, Somboon, Ariyadej, S, Ngo-Giang-Huong, N, Sophie Le Cœur, Trinh Duong, Kantipong, P, Pacharee Kantipong, Duong, T, Somboon Tansuphasawasdikul, Nicole Ngo-Giang-Huong, Tansuphasawasdikul, S, Thongpaen, Suchart, Ariyadej, Sriprapar, Ariyadej, Seiprapar, Program for HIV Prevention and Treatment Study Group, Study Group, Program for HIV Prevention and Treatment (PHPT), Buranabanjasatean, Sudanee, Marc Lallemant, Leenasirimakul, P, Lallemant, M, Buranabanjasatean, S, Le Cœur, Sophie, Ngo-Giang-Huong, Nicole, Leenasirimakul, Prattana, Gonzague Jourdain, Suchart Thongpaen, Kantipong, Pacharee, Sriprapar Ariyadej, Prattana Leenasirimakul, Thongpaen, S, Le Cœur, S, Ariyadej Sriprapar, Tansuphasawasdikul Somboon, Ariyadej, S., Lallemant Marc, Jourdain Gonzague, Kantipong Pacharee, Duong, T., Buranabanjasatean Sudanee, Thongpaen Suchart, Le Cœur Sophie, Buranabanjasatean, S., Leenasirimakul, P., Kantipong, P., Leenasirimakul Prattana, Duong Trinh, Ngo-Giang-Huong Nicole, Tansuphasawasdikul, S., Thongpaen, S.   +53 more
core   +1 more source