Results 11 to 20 of about 2,643,192 (369)
Leukemia remains incurable partly due to difficulties in reaching and maintaining therapeutic drug concentrations in the target tissues and cells. Next-generation drugs targeted to multiple cell checkpoints, including the orally active venetoclax (Bcl-2 ...
James Griffin+4 more
doaj +1 more source
Clinical determinants of early parasitological response to ACTs in African patients with uncomplicated falciparum malaria: a literature review and meta-analysis of individual patient data [PDF]
Background Artemisinin-resistant Plasmodium falciparum has emerged in the Greater Mekong sub-region and poses a major global public health threat. Slow parasite clearance is a key clinical manifestation of reduced susceptibility to artemisinin.
Alemayehu, Bereket H.+1 more
core +2 more sources
Objective Inhibiting preterm labour at extremely early gestations.Design Observational study. Case reports.Setting Perinatal Centre Lund University Hospital, South Sweden.Population Twenty‐five women (13 cases with intact membranes and 12 cases with ruptured) with threatened preterm labour and advanced cervical status before 26 completed weeks of ...
openaire +4 more sources
Combination inhaled steroid and long-acting beta-agonist in addition to tiotropium versus tiotropium or combination alone for chronic obstructive pulmonary disease (Review) [PDF]
Background The long-acting bronchodilator tiotropium and single inhaler combination therapy of inhaled corticosteroids and long-acting beta(2)-agonists are both commonly used for maintenance treatment of chronic obstructive pulmonary disease.
Appleton+10 more
core +1 more source
Combination Therapy in Hypertension
Editor’s Note: The American Society of Hypertension is publishing a series of Position Papers in their official journals throughout the 2008–2011 years. The following Position Paper originally appeared: JASH. 2010;4:42–50.The goal of antihypertensive therapy is to abolish the risks associated with blood pressure (BP) elevation without adversely ...
Alan H, Gradman+8 more
openaire +7 more sources
Combination Therapy Is the New Gene Therapy? [PDF]
International ...
Ronzitti, G., Mingozzi, F.
openaire +7 more sources
Combination therapy in the treatment of hypertension
Hypertension is a major preventable risk factor for atherosclerosis and ischemic heart disease. Although modern and effective antihypertensive drugs are available, most patients remain with a suboptimal blood pressure control.
Alberto Francisco Rubio-Guerra
doaj +1 more source
Combination Therapy of Sorafenib and Transarterial Chemoembolization in Management of Hepatoma [PDF]
Incidence of hepatocellular carcinoma (HCC) continues to increase in developing countries and rank 5th in male and 7th in female. Main cause being reported is chronic hepatitis B in Asian region. Treatment of choice for HCC is liver resection, however it
Gani, R. A. (Rino)+3 more
core +1 more source
Objective: To study the prescribing pattern of antipsychotic drugs in the outpatient department of psychiatry in Silchar Medical College and Hospital (SMCH) of Assam.
Pinaki Chakravarty+2 more
doaj +1 more source
Synthetic Lethality of Chk1 Inhibition Combined with p53 and/or p21 Loss During a DNA Damage Response in Normal and Tumor Cells [PDF]
Cell cycle checkpoints ensure genome integrity and are frequently compromised in human cancers. A therapeutic strategy being explored takes advantage of checkpoint defects in p53-deficient tumors in order to sensitize them to DNA-damaging agents by ...
A Besson+43 more
core +2 more sources