Results 11 to 20 of about 2,643,192 (369)

Design and Characterization of a Novel Venetoclax-Zanubrutinib Nano-Combination for Enhancing Leukemic Cell Uptake and Long-Acting Plasma Exposure

open access: yesPharmaceutics, 2023
Leukemia remains incurable partly due to difficulties in reaching and maintaining therapeutic drug concentrations in the target tissues and cells. Next-generation drugs targeted to multiple cell checkpoints, including the orally active venetoclax (Bcl-2 ...
James Griffin   +4 more
doaj   +1 more source

Clinical determinants of early parasitological response to ACTs in African patients with uncomplicated falciparum malaria: a literature review and meta-analysis of individual patient data [PDF]

open access: yes, 2015
Background Artemisinin-resistant Plasmodium falciparum has emerged in the Greater Mekong sub-region and poses a major global public health threat. Slow parasite clearance is a key clinical manifestation of reduced susceptibility to artemisinin.
Alemayehu, Bereket H.   +1 more
core   +2 more sources

Combination therapy [PDF]

open access: yesBJOG: An International Journal of Obstetrics & Gynaecology, 2005
Objective  Inhibiting preterm labour at extremely early gestations.Design  Observational study. Case reports.Setting  Perinatal Centre Lund University Hospital, South Sweden.Population  Twenty‐five women (13 cases with intact membranes and 12 cases with ruptured) with threatened preterm labour and advanced cervical status before 26 completed weeks of ...
openaire   +4 more sources

Combination inhaled steroid and long-acting beta-agonist in addition to tiotropium versus tiotropium or combination alone for chronic obstructive pulmonary disease (Review) [PDF]

open access: yes, 2011
Background The long-acting bronchodilator tiotropium and single inhaler combination therapy of inhaled corticosteroids and long-acting beta(2)-agonists are both commonly used for maintenance treatment of chronic obstructive pulmonary disease.
Appleton   +10 more
core   +1 more source

Combination Therapy in Hypertension

open access: yesThe Journal of Clinical Hypertension, 2010
Editor’s Note: The American Society of Hypertension is publishing a series of Position Papers in their official journals throughout the 2008–2011 years. The following Position Paper originally appeared: JASH. 2010;4:42–50.The goal of antihypertensive therapy is to abolish the risks associated with blood pressure (BP) elevation without adversely ...
Alan H, Gradman   +8 more
openaire   +7 more sources

Combination therapy in the treatment of hypertension

open access: yesDrugs in Context, 2018
Hypertension is a major preventable risk factor for atherosclerosis and ischemic heart disease. Although modern and effective antihypertensive drugs are available, most patients remain with a suboptimal blood pressure control.
Alberto Francisco Rubio-Guerra
doaj   +1 more source

Combination Therapy of Sorafenib and Transarterial Chemoembolization in Management of Hepatoma [PDF]

open access: yes, 2013
Incidence of hepatocellular carcinoma (HCC) continues to increase in developing countries and rank 5th in male and 7th in female. Main cause being reported is chronic hepatitis B in Asian region. Treatment of choice for HCC is liver resection, however it
Gani, R. A. (Rino)   +3 more
core   +1 more source

Prescribing pattern of antipsychotic drugs in the outpatient department of psychiatry in Silchar Medical College and Hospital, Assam

open access: yesOpen Journal of Psychiatry and Allied Sciences, 2016
Objective: To study the prescribing pattern of antipsychotic drugs in the outpatient department of psychiatry in Silchar Medical College and Hospital (SMCH) of Assam.
Pinaki Chakravarty   +2 more
doaj   +1 more source

Synthetic Lethality of Chk1 Inhibition Combined with p53 and/or p21 Loss During a DNA Damage Response in Normal and Tumor Cells [PDF]

open access: yes, 2013
Cell cycle checkpoints ensure genome integrity and are frequently compromised in human cancers. A therapeutic strategy being explored takes advantage of checkpoint defects in p53-deficient tumors in order to sensitize them to DNA-damaging agents by ...
A Besson   +43 more
core   +2 more sources

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