Results 31 to 40 of about 9,546,669 (393)
Node-positive breast cancer: Which are the best chemotherapy regimens? [PDF]
, 2008 Breast cancer-associated mortality has been significantly reduced since the 1990s, mainly because of early diagnosis and systemic therapeutic interventions.
Bauerfeind, Ingo +5 more
core +2 more sources
Journal of Managed Care Pharmacy, 2003 Adult Treatment Panel III (ATP III) guidelines recommend specific treatment targets for low-density lipoprotein cholesterol (LDL-C) levels according to an individual.s short-term and long-term risk for coronary heart disease (CHD). Therapeutic lifestyle changes are recommended for all patients at any level of risk for CHD.
openaire +2 more sources
Systems analysis of drug-induced receptor tyrosine kinase reprogramming following targeted mono- and combination anti-cancer therapy [PDF]
, 2014 The receptor tyrosine kinases (RTKs) are key drivers of cancer progression and targets for drug therapy. A major challenge in anti-RTK treatment is the dependence of drug effectiveness on co-expression of multiple RTKs which defines resistance to single ...
Bown, James L. +8 more
core +6 more sources
Combination therapy in combating cancer
OncoTarget, 2017 Combination therapy, a treatment modality that combines two or more therapeutic agents, is a cornerstone of cancer therapy. The amalgamation of anti-cancer drugs enhances efficacy compared to the mono-therapy approach because it targets key pathways in a
R. Mokhtari +6 more
semanticscholar +1 more source
Nanocarrier-based drug combination therapy for glioblastoma
Theranostics, 2020 The current achievements in treating glioblastoma (GBM) patients are not sufficient because many challenges exist, such as tumor heterogeneity, the blood brain barrier, glioma stem cells, drug efflux pumps and DNA damage repair mechanisms.
Mengnan Zhao +4 more
semanticscholar +1 more source
Combination Therapy for Myelomatosis [PDF]
BMJ, 1974 Twenty-eight patients with multiple myeloma have been treated with a quadruple chemotherapeutic regimen consisting of 1, 3 bis (2-chloroethyl)-1-nitrosourea (BCNU), cyclophosphamide, melphalan, and prednisolone. Nineteen new patients and nine who had escaped from previous single-agent therapy were included in the study.
I. W. Delamore, L. Azam
openaire +3 more sources
Combination therapy of hypertension
Медицинский совет, 2015 The article is a short overview of articles related to the prescription of combination antihypertensive therapy. The focus is on the evidence of administration of a fixed combination - lercanidipine plus enalapril, which is characterized by a high ...
O. O. Bolshakova
doaj +1 more source
Engineering blood exosomes for tumor-targeting efficient gene/chemo combination therapy
Theranostics, 2020 Rationale: Developing an effective nanoplatform to realize 'multi-in-one' is essential to broaden the therapeutic potential of combination therapy.
Qi Zhan +12 more
semanticscholar +1 more source
Combination Antithrombotic Therapies [PDF]
Circulation, 2010 Atherothrombosis is the major pathophysiological process responsible for the occurrence of severe ischemic events in patients with cardiovascular diseases. In the United States, atherothrombosis strongly influenced mortality in 2004: One in 2.8 deaths was due to CVD, 1 in 5 deaths to coronary heart disease, and 1 in 17 deaths to stroke.1 Because ...
Paul A. Gurbel, Udaya S. Tantry
openaire +3 more sources
Omadacycline Potentiates Clarithromycin Activity Against Mycobacterium abscessus
Frontiers in Pharmacology, 2021 Mycobacterium abscessus is a difficult respiratory pathogen to treat, when compared to other nontuberculus mycobacteria (NTM), due to its drug resistance.
Bui Thi Bich Hanh +7 more
doaj +1 more source